6123 resultaten
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
1. The primary research inquiry being raised concerns anaesthesia related causes: Is it possible that adapting an amount of Sevoflurane, from 1 MAC (minimum alveolar concentration) (2,5 vol%) to ½ MAC (1,25 vol%) in an MRI scan can reduce the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
this study hypotheses that EEG does not predict future seizures. If correct abandoning routinely EEG will lead to a reduction in health costs and patient/family burden. Furthermore, neurocognitive development will be investigated two years after…
Treatment with a probiotic dairy product releives symptoms in Irritable Bowel Syndrome patients. It also improves quality of life of the patients, and has an positive effect on the composition of the microbiota. Cytokine stimulation profiles will…
Different processing of milk products will have impact on metabolic availability of amino acid
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
5 and 10 grams of a protein hydrolysate effectively increase insulin secretion and lowers plasma glucose levels after a carbohydrate load in type 2 diabetes mellitus (DM-2)
Treatment with rhEPO has no effects on performance parameters measures by exercise tests.
Infliximab counteracts the increased synthesis of tumor necrosis factor alpha (TNF-alpha), after which inflammation will decrease and recovery of the disease occur.
We hypothesize that PEMF-treatment will be of additional value after the primary arthroscopic treatment of an OD, and the resumption of sports can be both improved and accelerated.
Elective laparoscopic appendectomy is a usefull procedure in patients with chronic or recurrent right lower abdominal pain.
Statin-treatment has been shown to normalize the learning- and attention deficits in NF1 +/- mice by decreasing Ras activity. The fact that statins are effective in NF1 mice, combined with their very good safety profile, makes them an ideal…
This study evaluates the beneficial effects of exercise training with or without oral anti-diabetic medication in patients with coronary artery disease (CAD): PCI or CABG in stable CAD, or post STEMI and post non-STEMI patients who have pre-diabetes…
At least 90% of the subjects, with 95% confidence, will tolerate the test formula.
Acclydine is a plant sourced alkaloid which has effects on protein structure and metabolism. In particular it leads to the activation of the pituitary to increase release of growth hormone. The GH axis has been shown to be disturbed in CFS, so this…