3292 resultaten
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…
The guided internet-based behavioral activation intervention is expected to show favorable effects in comparison to online-delivered minimal psychoeducation without support in participants with depressive disorders, as shown by the results on…
The intervention will result in: - higher observed sensitivity and more positive attitudes towards sensitive caregiving in professional caregivers - lower cortisol levels, higher wellbeing and more attachment security in infants - less separation…
An activity stimulation program improves mobility performance and fitness in children with cerebral palsy.
We aim to study the use of braces for thoracolumbar burstfractures, not only by measuring the functional scores and the effect of the bracing or functional treatment on the increase in kyphosis angle, but also on (health related) quality of life and…
Multiple rounds of S(+)-ketamine infusions will give more profound and prolonged pain relief compared to a single infusion of S(+)-ketamine.
1. A multidimensional lifestyle intervention, including aspects of increased awareness, motivation, self-management, diet, exercise, and a supportive environment, improves or prevents deterioration of the cardiometabolic risk factors of SMI…
It is important that parents quit smoking, as this has serious detrimental effects on their own health and their children's health. The majority of parents want to quit smoking. However, many quit attemts are unsuccessful. Recently a proactive…
Prolonged ingestion of chocolate milk during a training program improves the sports performance parameters in badminton athletes more than control.
A 16-week multidisciplinary lifestyle program, based on (1) a WFPD, (2) exercise and (3) stress management H0: has no effect on the WOMAC in patients with hip- and/or knee osteoarthritis and metabolic syndrome, in comparison with usual care. H1:…
Perturbation-based gait training improves dynamic stability and reactive responses in daily life in older adults. Therefore, the risk of falling can be reduce by training.
In the Netherlands, case managers play an essential role in the care chain for people with dementia living in the community. Because the profession has just been started, there is a lack of evidence-based practice to provide treatment for agitation…
We expect that parents involved in the program (as compared to controls) will be more involved in high qualitative communication on alcohol topics, have more confidence in discussing alcohol matters and greater efficacy to prevent their children…
Compression therapy is not necessary after VNUS. Patients receiving no compression therapy after VNUS will have similar outcomes in post-operative pain, oedema, and HRQOL, post-operative complications, time to full recovery.
Compressive occlusal loading of a space between composite and tooth material will lead to an increase in lesion depth and mineral loss in these samples.
Custom made orthotic insoles by a podiatrist are (cost)effective in reducing pain and improving function in patients with plantar fasciitis compared to sham orthotic insoles and education alone.
Young people with a psychotic disorder have the same social goals as their healthy peers, but their social networks are smaller, they participate less often in leisure activities and are less successful in work and education. This impairment in…
We hypothesize that the new AFI-III system – compared to the conventional AFI-II – enhances the distinction between early neoplasia and inflammation in BO and thus reduces the amount of false positive lesions, allowing for targeted sampling and…