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This is an exploratory study, but we expect to find that the apparent diffusion coefficient on diffusion-weighted MRI and SUVmax on FDG-PET are able to differentiate between tumor tissue and treatment effects.
We hypothesize that serum inflammatory markers, BBB integrity and PHO are associated with perihematomal inflammation.
The purpose of this pilot study is to describe the changes in NK cell percentages and therefore is hypothesis generating rather than hypothesis testing
We hypothesize that the prediction score can discriminate between low-risk and high-risk patients with moderate-good accuracy.
Frailty causes disability independently of (sub)clinical diseases. Frailty assessment has the potential to improve burn care in middle-aged and elderly patients (≥50 years). If diagnosed in time improvement is possible which enhances both burn care…
Home blood pressure measurement and 24 hour ambulatory blood pressure monitoring will be in good agreement with each other
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…
Investigating the taste preference of patients directly after surgery in the PACU, and adjusting the available food products to the outcomes, will help to increase the dietary intake in postoperative patients in the PACU and thereby positively…
Conservative treatment: 1. Most patients accept/improve with regards to their complaints
CFS-NL is a good tool to score frailty in elderly burn patients
The HRUS protocol to distinguish the anatomical type of Lister's tubercle is valid protocol and has a good inter-rater reliability
We will be able to develop a discomfort recognition algorithm for physiological responses of typically developing (TD) children and children with CP (only if the results of TD children are promising) to discomfort induced by the use of technological…
Patients with inflammatory bowel disease (IBD) carry an increased risk of colorectal cancer (CRC). To detect and remove dysplastic precursors before progressing to CRC, IBD patients receive regular surveillance colonoscopies with fixed intervals…
The number of pretreatment HRDs on OCT can predict response to intravitreal anti-VEGF therapy in DME.
- Language and non-language executive control abilities are positively associated in bilingual and monolingual individuals, with and without aphasia. - Bilingual and general language control abilities are positively associated in bilingual…
We hypothesized that the use of a minimal invasive non-fusion bipolar posterior spinal implant (Nemost growing domino) can both correct and brace the spine internally and adapt balans and or distraction as the idiopathic scoliosis patient grows.
The change in mean diffusion coefficient early during treatment, improves the performance of a prognostic model for LRC of HPV negative oropharyngeal cancer patients.
Primary hypotheses: - Responders (CGI-SCH degree of positive symptom change rating of 1 or 2) have significantly higher [18F]-DOPA influx (Ki) values in the whole striatum and its associative and sensorimotor subregions compared to non-responders (…
Nephrogeriatric assessment will be beneficial in identifying patients for whom conservative care might be a better option (QoL, clinical outcomes, costs) than starting dialysis.