14 resultaten
Primary objective: - To evaluate the safety and tolerability of NT-0167 in healthy volunteers Secondary: - To evaluate the pharmacokinetic (PK) profile of NT-0167 in healthy volunteers after the administration of single ascending (SAD) and multiple…
The size of intrinsic foot muscles is associated with gait biomechanics and balance in older adults
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
to further evaluate and monitor the safety and performance of the “BasIQ-4®” in a population of women delivering in general hospitals in The Netherlands when used as intended
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
We hypothesize that FMT from a healthy donor will modulate the microbiome of the pouch of patients with ulcerative colitis, and will thereby resolve the inflammation of the pouch.
A subset of rheumatoid arthritis (RA) patients harbour antibodies against several post-translational modifications and are frequently positive for rheumatoid factor. The exact pathophysiology of the development of the autoantibody response and of RA…
It is hypothesized that the FitMáx© questionnaire is a valid clinical assessment tool for CRF compared to the gold standard, a cardiopulmonary exercise test. Moreover we believe the FitMáx© to be fairly accurate in the preoperative risk assessment…
Treatment with chloroquine or hydroxychloroquine of adult patients admitted with moderate to severe COVID-19, a NEWS-2 score ≤5, reduces the proportion of patients who show progression of their disease defined as a NEWS-2 score ≥ 7(22), admission to…
The aim of the study is to gather information regarding COVID-19 infections during pregnancy. Up to now, little is known about COVID-19 during pregnancy.
Hoofd doel:Levert toevoeging van azithromycine aan standaardbehandeling met chloroquine op dag 7 een hoger klinisch genezingspercentage op dan behandeling met alleen chloroquine bij patiënten met COVID-19.Er is sprake van genezing wanneer de…
Deze studie zal onderzoeken of het veilig is om immunomodulerende therapie te staken bij patiënten met multiple sclerose die de afgelopen vijf jaar geen tekenen van inflammatoire ziekteactiviteit hebben vertoond.Primaire onderzoeksvraag:- Kan…
Het primaire doel van deze studie is om aan te tonen dat in oesofagaal adenocarcinoom de onderdrukking van stroma-activiteit gemeten met ADAM12 door de ILR6 inhibitor tocilizumab de effectiviteit van chemoradiatie vergroot zoals gemeten met de…