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The peripheral immune response is changed following a traumatic spinal cord injury.
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
Oral bisphosphonate supplementation or the MMR vaccine can be used as immune potentiators when simultaneously administered with BCG, to further amplify the BCG-induced trained immunity response and maximize potential protective effects against COVID…
Week 8 clinical outcome can be predicted using baseline and week 2 clinical and medical imaging data
We hypothesize that the greater part of professional cyclist will be diagnosed with osteopenia or osteoporosis. Furthermore, we expect that low bone mineral density will not be normalized after the active career.
Cognitive remediation focused on executive functioning for patients with bipolar disorder improves executive functioning on (1) personal goals in daily life, and (2) general well-being. Exploratory hypotheses: - Cognitive remediation focused on…
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High BMI is associated with worst prognosis after SARS-CoV2 infection
The functional architecture of the cerebral network controlling breathing is impaired in patients with myotonic dystrophy type I.
Primary endpoint: Validate the VBMEG algorithm using hd-EEG source reconstruction compared to fMRI activity.
Based on Faber ea. 2006, we expect that the effectiveness of ‘In Balans’ can be replicated and extended in a group of community-dwelling pre-frail and non-frail older adults with an increased risk of falls, with a significant reduction of the number…
In is hypothesized that the glycemic response to standardized snacks differs within subjects between different times of the day
The key objective of this study is to investigate whether modulation of cortical excitability by AEDs (such as levetiracetam), can be reliably measured using TMS-EMG and TMS-EMG in patients with epilepsy. Thereby, this study will assess whether TMS-…
Effect of parental restrictiveness on sweetness preference and intake of sugary foods/drinks of the children
Studies have described an altered bacterial diversity in the gut of women with IBD as compared to healthy controls. Infants born to mothers with IBD have shown to have lower diversity and altered gut microbiome at least until age 3 months. This…
Curcumin is expected to have a positive effect in the composition of gut microbiota and the measurable outcomes of this change in composition.
Radiation side-effects can be predicted by irradiating patient specific lung epithelial organoids in vitro.
The erector spinae plane block is non-inferior to paravertebral block with regards to pain relief and use of opioids in in breast cancer patients undergoing mastectomy with immediate reconstruction.
A priori, we hypothesize that fatigue is highly prevalent in patients with chronic diseases and little is known on effective treatment strategies to reduce fatigue.