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A 10% point difference between the intervention group and control group in IDM is expected. The sample size calculation is based on a worst-case scenario with regard to precision. For a binomial distribution, the widest distribution and thus largest…
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
The primary objective is to investigate the feasibility of using intra-arterial ICG preoperatively to allow for liver segment visualization during anatomical liver resection.
There is no difference in radiographic parameters of immediate loading and delayed loading of single posterior tooth implants in healed sites.
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
Doctors exposed to aerosol generating procedures (AGP) are more at risk of contracting COVID-19 than those not exposed to AGP
To evaluate clinical outcome, 30-day mortality, 5 year mortality and related costs of elderly burn patients in specialized burn care. To evaluate factors related to poor outcome, including12-months mortality, discharge destination and 30 days…
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
Oral bisphosphonate supplementation or the MMR vaccine can be used as immune potentiators when simultaneously administered with BCG, to further amplify the BCG-induced trained immunity response and maximize potential protective effects against COVID…
We hypothesize that the greater part of professional cyclist will be diagnosed with osteopenia or osteoporosis. Furthermore, we expect that low bone mineral density will not be normalized after the active career.
Investigating the taste preference of patients directly after surgery in the PACU, and adjusting the available food products to the outcomes, will help to increase the dietary intake in postoperative patients in the PACU and thereby positively…
We hypothesize that serum inflammatory markers, BBB integrity and PHO are associated with perihematomal inflammation.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
CFS-NL is a good tool to score frailty in elderly burn patients
We will be able to develop a discomfort recognition algorithm for physiological responses of typically developing (TD) children and children with CP (only if the results of TD children are promising) to discomfort induced by the use of technological…
We hypothesize that especially the reward centres of the brain respond much stronger to processed food in BED, whereas much smaller differences are expected after consuming unprocessed food.
The hypothesis is that random assignment to C1-INH in patients with moderate and severe TBI will experience a reduction in ICP directed therapy intensity levels (TIL) compared to random assignment to placebo (difference of 2.2). Secondary, if…
The survival of extensive direct composite restorations involving one or more cusps after up to 13 years will be sufficient
As for now, 177Lu-PSMA has not been widely studied in patients within earlier phases of disease such as lymph node metastatic HSPCa. In theory, RLT could be more effective in low volume disease because of the very high tumor uptake of radioligands…