4666 resultaten
To improve dosing strategies and minimize adverse effects, the current TDM should be optimized. We advocate that PD-based instead of PK-based therapeutic drug monitoring, by using clinically relevant immune tests to quantify the immunosuppressive…
We hypothesize that poor and intermediate CYP2C19 metabolizers using clopidogrel after endovascular aneurysm repair (EVAR) have an increased risk of adverse clinical events related to arterial thrombosis.
Our hypothesis is that patients with micro and macrovascular potentially have a different geriatric profile (cognitive function, physical function, ADL dependency, negative outcomes)
A multimodal revalidation program after surgery ensures patients to start chemotherapy in time and ensures patients to better tolerate adjuvant chemotherapy.
TEMPO zal i) conventionele dosisreductie direct vergelijken met ii) geleidelijk afbouwen bij patiënten met een depressie in remissie, die ofwel het antidepressiva paroxetine (PAR) of venlafaxine (VLX) gebruiken. We zullen het aantal patiënten dat…
We hypothesize that our AF algorithm can detect AF events based upon the one-lead ECG data that Afi has collected with a sensitivity of 95% and a specificity of 80%.
Patients with inflammatory bowel disease (IBD) carry an increased risk of colorectal cancer (CRC). To detect and remove dysplastic precursors before progressing to CRC, IBD patients receive regular surveillance colonoscopies with fixed intervals…
The hypothesis is that random assignment to C1-INH in patients with moderate and severe TBI will experience a reduction in ICP directed therapy intensity levels (TIL) compared to random assignment to placebo (difference of 2.2). Secondary, if…
It is hypothesised that the bespoke smoking intervention is more effective than usual care to reduce nicotine dependence and smoking for people with severe mental illness in FACT-teams in the Netherlands.
We hypothesise that open and endoscopic cubital tunnel release have a different effectiveness in treating cubital tunnel syndrome in both primary and secondary outcomes. Since the RCTs performed were of moderate-quality and consists of a relatively…
The purpose of this pilot study is to describe the changes in NK cell percentages and therefore is hypothesis generating rather than hypothesis testing
We hypothesis that collagen supplementation augments the benefits of jumping exercise for bone metabolism.
We hypothesize that the fertility enhancing effect of OSCM during HSGs is also present during THL.
We hypothesize that especially the reward centres of the brain respond much stronger to processed food in BED, whereas much smaller differences are expected after consuming unprocessed food.
We hypothesize that the prediction score can discriminate between low-risk and high-risk patients with moderate-good accuracy.
We assume that hair removal treatment with the Splendor-X SMART is feasible.
No difference exists in clinical, microbiological and radiographical outcomes in the surgical treatment of peri-implantitis using air-polishing or handinstrumentation
There is no hypothesis. We will retrospectively describe patient status, surgical practice and patient outcome during and directly after the peak of the COVID-19 outbreak.
We hypothesize that NIRF angiography has added value for peri-operative evulation of flap design and free flap perfusion and subsequently we hypothesize that hyperspectral imaging and thermal imaging have added value for monitoring free flap…
Primary Outcome: Targeted LV lead delivery results in a higher proportion of in-target pacing when compared to the control group. Secondary Outcomes: Targeted LV lead delivery results in more clinical benefit when compared to the control group.