2298 resultaten
Benign liver tumors and cysts carry a significant burden on the quality of life in some cases. Apart from impairing symptoms, psychological burden might provide sufficient ground for surgical intervention. There is a variable approach to them…
We hypothesize that in critically ill patients, measuring the anti-factor-Xa randomly in a 3 to 5 hours timeframe, may introduce a significant variation in the measured anti-factor-Xa and can seriously underestimate the real peak anti-factor-Xa.
The hypothesis is that the injury rate, severity and burden of injury over one-season is lower among youth volleyball players using ‘VolleyVeilig’ than among youth volleyball players not using ‘VolleyVeilig’ (volleyball as usual).
A 12 weekly computer-tailored coaching program reduces sedentary behavior. Perceived bodily pain, mental health, vitality, stress, and performance are expected to lower by the means of reduced sitting time.
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Exploratory study investigating the efficacy of the currently recommended dosing regimen of ciprofloxacin prophylaxis in patients treated for haematological malignancies.
Based on most recent insights in AAV treatment, the present study intends to evaluate whether combining rituximab with cyclophosphamide is superior to current standard of care with rituximab only to induce a favorable immunological state of MRA in…
Interventions to promote indicator condition-guided testing for HIV in the hospital will facilitate earlier identification of HIV infection and therefore ultimately help stop HIV
To explore the positive, negative or lack of effect that these components have (isolated and combined) on tinnitus disability.
Prehabilitation may improve functional capacity and nutritional status before surgery, resulting in enhanced recovery after surgery, reduced complication rates, improved quality of life and patient’s overall outcome. Patients with non-small cell…
PENELOPE onderzoekt welk cohort van een sub-populatie hoog risico patiënten na een Acuut Coronaire Syndroom (ACS) bij het strikt volgen van de richtlijn in drie stappen niet de beoogde lipide streefwaarden behaalt. De studie volgt de reguliere…
Psychological and communication theories predict that COMBO improves values deliberation, compared to a single tool. Alongside, patient decision outcomes such as being decisive, being knowledgeable, and being clear about values will improve. As…
It is hypothesized that GSH CBT-E is superior to the waiting list condition with regard to a decrease in eating disorder pathology and clinical impairment. GSH CBT-E is also expected to be superior to the waiting list with regard to increase in the…
The intervention with Transcranial Direct Current Stimulation (tDCS) on the Ventromedial Prefrontal Cortex (vmPFC) in comparison with the treatment as usual will improve empathic abilities and reduce violent behavior in forensic substance use…
Patients who undergo aortoiliac surgery for occlusive disease have higher rates of SSI compared to aneurysmal disease.
To identify (both primary and acquired) resistance mechanisms to chemo-immunotherapy (obtained by less invasive procedures (NGS on ctDNA in blood & urine, exhaled breath or microbioma in stools alone or in combination)) and provide new…
90-day treatment with a selected probiotics mixture can reconstitute the microbiome diversity after antibiotic treatment for community-acquired pneumonia.
We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to…
Based on clinical experience in our multidisciplinary team caring for children with PAH and CHD, we expect that children with PAH and their families suffer from decreased psychosocial QoL compared to healthy norms. We expect psychosocial…
Our hypothesis is that in patients with no-option critical limb ischemia, a treatment with pDVA is a feasible, safe and a clinically effective approach.