1053 resultaten
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
Fatigue is expected to be the most prevalent symptom in patients with ILD (IPF and sarcoidosis), next to dyspnoea. Frequency of moderate to severe fatigue in patients with ILD is unknown. In addition, possible correlates of fatigue, including age,…
Gut-homing lymphocytes play a role in the development and maintainence of perianal fistula in Crohn's disease patients.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
Our hypothesis is that adolescents that have been educated on an 'enjoy being fit' elementary school exhibit healthier scores than adolescents that have been educated on a regular Elementary school on the set of outcome variables. However…
Deep brain stimulation (DBS) targeted at the ventral anterior limb of the internal capsule (vALIC) is an effective treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, effective DBS for these patients requires relative…
Parenting is essential for the upbringing of social, mentally and physically healthy children. Parenting interventions can support parents in this process. In general, parent training programs have a positive influence on various outcomes related to…
Patients with ADAM12 > 203 ng/mL in their serum benefit from the addition of biweekly tocilizumab for 3 doses to neoadjuvant chemoradiation before esophagectomy
Nicardipine might decrease adverse maternal and neonatal outcome due to its pharmacokinetics and fewer side-effects.
We anticipate that students who will receive the Internet-based intervention based on their symptoms will have high satisfaction and show high adherence to the program. We also expect to find significant improvements in symptoms of stress /mood and…
We expect an increased bone mineral density in the calcar region compared to the other ROI’s. Furthermore, we expect early detection of decreased mineral density of the femoral head in patients developing osteonecrosis of the femoral head.
We hypothesize that providing feedback to hospitals will reduce practice variation
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
Given the high prevalence and burden associated with sexual problems and the existence of barriers to seek treatment among gynaecological cancer patients, there is a clear need for a brief, inexpensive and effective psychosexual rehabilitation…
The main objective of this study is to investigate the effectiveness of BEAR (a parent training combining e-learning and home visits) compared to care-as-usual (CAU) in young children (12-30 months) who are at risk of developing ASD, in a cluster…
We hypothesize that implementation of the new post-transplantation program will result in: - Decreased renal function decline (improved graft survival) - Improved medication adherence - Improved tacrolimus exposition - Improved feeling of patient…
Drug-induced Sleep Endoscopy with cocomittant jaw thrust maneuver is a suitable predictor for succes of oral appliance treatment.
It is hypothesized that the E-health self-management treatment results in lower impact of the disease on daily life, primarily a lower level of distress, in comparison to care as usual. As secondary objectives the effectiveness of the treatment on…
The aim of this study is to investigate the non-inferiority of perioperative continuation of aspirin patients undergoing spinal surgery, compared with the current policy of perioperative discontinuation of aspirin.