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Het doel van deze studie is om het effect van Artiss, in vergelijking met onze standaard zorg, te analyseren. Hierbij wordt gekeken naar seroomvorming en de hoeveelheid seroom na het oogsten van een LD flap, welke wordt gebruikt bij een directe…
Doel van het onderzoek is het vergelijken van de tunnel positie voor AMP, TLS en TT reconstructie technieken. Ook zal er gekeken worden naar de relatie van de positionering en de slijtage van de tunnels.
The purpose of the activity and heart rate monitor is to measure and track movement (acceleration) and heartbeat, and derive a number of health-related parameters, which can serve as basis for behavioral change programs leading to e.g. a healthier,…
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
Tumor-positive lymph nodes in patients with early EAC can be accurately detected through a sentinel node procedure.
We hypothesize that liraglutide treatment, initiated before cardiac surgery, is effective in lowering the number of patients needing perioperative insulin adjustments and reducing the total amount of insulin needed in the perioperative period when…
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
The detection rate of the ICG method to identify the SLN in breast cancer patients is not inferior to the standard 99mTc method.
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
1. The addition of moderate positive end-expiratory pressure (PEEP, 7.5 cmH2O) to high inspiratory fractions of oxygen can either improve oxygenation or reduce respiratory rate, or both, in patients with severe Covid-19 pneumonia 2. The application…
We hypothesize that instillation of a radiopaque hydrogel before full thickness closure of the lumpectomy cavity will reduce inter-observer variability during target definition and improve patient setup accuracy for boost or partial breast…
Implementation of UCR as diagnostic marker for fetal compromise in SGA improves long-term neurodevelopmental outcome by identifying fetuses with fetal growth restriction (FGR) within the SGA group who will benefit from earlier delivery, improving…
The objective is to assess whether myocardial microvascular perfusion and myocardial energy metabolism is impaired in HFpEF patients. Additionally we will evaluate whether endothelial dysfunction is associated with diminished myocardial perfusion (e…
1. Leadless Pacemaker (LP) therapy is superior to current standard-of-care (SOC) with regard to procedure-related complications in Transcatheter Aortic Valve Replacement (TAVI) patients who develop conduction abnomalies (CA). 2. LP therapy reduces…
Common colds have a significant impact on individuals, health care and economy. Functional food ingredients can reduce incidence, duration and severity of common respiratory tract infections in healthy elderly and adults. We hypothesize that test…
The brace is able to restrict the movement that pose a risk for hip displacement after total hip replacement surgery
We hypothesize that percutaneous edge-to-edge mitral valve repair using MitraClip reduces left ventricular end diastolic volume and improves myocardial perfusion.
The majority of patients admitted outside a dedicated Burn Center will have a maximum of 10% Total Body Surface Area burned.
The physical activity condition will show a significantly stronger decrease in PTSD symptoms from pre- to post-treatment, compared to the active control condition
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…