2645 resultaten
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The aim of the study is to investigate the underlying mechanisms of gastroesophageal reflux and gastroesophageal reflux symptoms in treated achalasia patients. It is hypothesized that gastroesophageal reflux symptoms in treated patients with…
Two doses of the Coronavirus virus-like particle subunit vaccine ABNCoV2 in SARS-CoV-2-naïve healthy adults is safe and well tolerated.
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy with an acceptable toxicity profile.
Postoperative pain management by using either regional continuous PVB or single shot ICNB is non-inferior to TEA regarding pain in patients undergoing thoracoscopic anatomical lung resection. Regarding QoR after surgery the unilateral regional…
The microcirculation can be a supportive non-invasive biomarker for making clinical decisions and even help to predict sepsis and mortality in the Neonatal Intensive Care Unit.
We hypothesize that the HINTS+ test is more reliable than early MRI imaging in patients with acute onset continuous dizziness. As a result it is hypothesized that HINTS+ clinical examination leads to lower costs and an improvement in Quality of Life…
To find out if intravenous MSC is a safe treatment for children with therapy-resistant JIA
At least 90% of the subjects, with 95% confidence, will tolerate the test formula.
N/A
the quality of consultation can be improved
Het primaire doel van het onderzoek is om te onderzoeken of veranderingen over de tijd in monitorende metingen van cognitie en gedrag gerelateerd zijn aan functionele uitkomsten in pediatrische oncologie groepen. Overige doelen zijn het onderzoeken…
Simular outcomes in patients with 4 implants compared with patients with 6 implants with respects to peri-implant bone level stability
It is hypothesized that respiratory depression from the opioid oxycodone will increase with concomitant administration of alcohol. Furthermore it is hypothesized that the increase in respiratory depression is not only dependent on the dosage of…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
It is hypothesized that use of the 'Versterk je Enkel' App will increase compliance to the neuromuscular program and, consequently, will decrease ankle sprain recurrence incidence.
By reducing the interval between thyroidectomy and radioiodine ablation therapy in patients sick leave time of the patients can be reduced and the quality of life improved. Furhermore costs will for society will be lower.
The NTX intervention training leads to significant increase in both near and far transfer outcomes, in comparison with the effects of a training of an active control group.