1258 resultaten
Based on current literature we hypothesize that mindfulness based stress reduction training reduces psychological distress and improves 'positive mental health' in medical interns. Possibly MBSR can prevent psychological distress in the…
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
1. Inhaltion of tobramycin containing aerosols using the INeb® in the TBM mode is less effective as inhalation of in the TIM mode; 2. The amount of deposition is correlated to the systemic Area Under the Curve of tobramycin after inhaltion of…
The aim of the study is to compare the effectiveness of tocolysis with Nifedipine or Atosiban in pregnant women with threatened preterm labour with a gestational age between 25 – 34 weeks. We will look at neonatal mortality and morbidity, duration…
Ischemic postconditioning leads to a quicker recovery of kidney function by decreasing ischemia-reperfusion injury of the graft.
The primary objective of this study is to demonstrate that contact isolation of patients colonised with ESBL-producing Enterobacteriaceae in a multiple-occupancy room is not inferior to contact isolation in a single-occupancy room with respect to…
The hypothesis to be tested is the feasibility of arm A and arm B.
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Remote ischemic preconditioning (RIPC) has been shown to attenuate myocardial damage in cardiac surgery. We hypthesize that RIPC induced cardioprotection is associated with an increased amount of mitochondrial hexokinase.
The aims of the study are: 1. To compare the effectiveness of Cognitive Behavioral Therapy (CBT) for anxiety disorders between children with ASD and children without ASD; 2. To compare the (cost-) effectiveness of CBT to Treatment As Usual (TAU) for…
Oxytocin administration leads to stronger empathic reponses and faster emotional processing.
Specific areas of language production are affected in children and adolescents with classic galactosemia, in particular syntactic production. Further, it is hypothesized that the galactosmic patients will show a profile of general cognitive…
Dose reduction and withdrawal is non inferior to continuation of adalimumab or etanercept in RA patients with respect to disease activity.
Scar defect may give complications on long term. Study is to investigate if the defect is detectable with ultrasound.
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The use of platelets in addition to mucosa advancement flap in the treatment of complex peri-anal fistula will reduce the recurrence rate of these fistulas.
In RA patients that achieved disease remission by treatment with the combination of a csDMARD and anti-TNF, there is a difference in (cost-)effectiveness when medication is tapered according to strategy A (csDMARD first) compared to strategy B (anti…
Budesonide does not alter the exposure of cabazitaxel in castrate resistant prostate cancer patients.
Consumption of slowly digestible starch is implicated with a decreased risk for the development of obesity, insulin resistance and Type 2 diabetes (T2DM). Underlying mechanisms of this beneficial effect are not yet elucidated. The objective of this…
Acetaminophen is effective in treating self-reported sleep problems, in particular insomnia.