1803 resultaten
The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
THC causes changes in resting state brain activity that can be visualized by fMRI
In this study we will compare three method to assess the magnitude of the ventilatory response; our hypothesis is that different methods will yield different results.
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
To compare the clinical and cost-effectiveness of pelvic floor muscle training versus TVT/TVT-O surgery as primary treatment of moderate to severe female urinary incontinence.
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
In lungcancer bone metastases appear frequently en they are an important cause of pain. The expectation is that Bondronat® gives a fast pain reduction. In this phase II study will be examined whether this fast pain reduction indeed occurs and if…
The hypothesis is that stratification of the referred population by the two referring screening radiologists using a validated design (BI-RADS, screening variant) can lead to a fast track workflow with only imaging tools, which would enable us to…
Structural imaging is more sensitive to early (progression) detection than functional measurements (i.e. visual fields).
What is the effect of carbohydrate infusion on food choice, food intake, satiety, hormones, dependent on the time of day and segment of the small intestine?
Ho: the life birth rate in patients after SET with only morphological embryo selection is equal to patients with metabolomic profiling added to morphological selection. H1: the life birth rate in patients after SET with only morphological embryo…
We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
A 7-day course of antibiotic treatment is non-inferior to a 14-day course in febrile urinary tract infection.
rTMS suppresses neural circuits using a pulsed magnetic field which temporarily excites or inhibits a certain brain area. It is thought that tinnitus is generated in the brain as a result of functional reorganization of auditory neural pathways and…
Discontinuation of long term use of antipsychotics for behavioral symptoms in patients with mental retardation does not lead to deterioration in mental functioning.
A first hypothesis is that an advanced quality improvement program (AQIP) significantly improves clinical outcomes in persons with type 2 diabetes compared to a usual quality improvement program (UQIP). The second hypothesis is that persons with…