4139 resultaten
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…
Half dose Urokinase (50.000IE/h) will significantly reduce hemorrhagic complications compared with the standard dose Urokinase (100.000IE/h) with comparable technical success rate
Better and faster recovery of arm/hand for patients treated with rTMS
Patients will improve significantly on OCD symptoms and general functioning.
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
Stromal Vascular Fraction enriched lipofilling in combination with Platelet Rich Plasma (PRP) increases skin quality improvement as compared to lipofilling in combination with PRP alone.
THC causes changes in resting state brain activity that can be visualized by fMRI
In this study we will compare three method to assess the magnitude of the ventilatory response; our hypothesis is that different methods will yield different results.
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
To compare the clinical and cost-effectiveness of pelvic floor muscle training versus TVT/TVT-O surgery as primary treatment of moderate to severe female urinary incontinence.
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
The outcome in patients with removal on demand is not inferior to the outcome in patients with routine removal. By omitting routine removal a reduction in costs will be achieved
Acute stress and increased levels of dopamine in the brain will lead to a shift from goal-directed behaviour to habitual behaviour. The shift will coincide with a change in functional connectivity between brain areas governing goal-direct and…
In lungcancer bone metastases appear frequently en they are an important cause of pain. The expectation is that Bondronat® gives a fast pain reduction. In this phase II study will be examined whether this fast pain reduction indeed occurs and if…
A decision aid about postoperative epidural analgesia will improve patients' knowledge.
The primary objective of this study is to review the prevalence of pelvic organ prolapse after laparoscopic hysterectomy compared to vaginal hysterectomy. Because the uterosacral ligaments are the important structure for vault suspension after…
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up