4008 resultaten
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
The implementation of the delirium part of the Vulnerable elderly project will improve when nurses have completed an e-learning tool regarding delirium care for elderly patients.
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
A levonorgestrel releasing intrauterine system (LNG-IUS) and endometrial ablation are two frequently used methods for the treatment of menorrhagia, of which the first can be applied by a general practitioner or a gynaecologist, whereas the second is…
Based on current literature we hypothesize that mindfulness based stress reduction training reduces psychological distress and improves 'positive mental health' in medical interns. Possibly MBSR can prevent psychological distress in the…
1. Describe concomittant electrical activation of endocardial and epicardial layers of atrium that have been shown in animal models to be dissociated, and to be involved in the perpetuation of AF; 2. Describe with a density mapping catheter the…
THC causes changes in resting state brain activity that can be visualized by fMRI
In this study we will compare three method to assess the magnitude of the ventilatory response; our hypothesis is that different methods will yield different results.
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
To compare the clinical and cost-effectiveness of pelvic floor muscle training versus TVT/TVT-O surgery as primary treatment of moderate to severe female urinary incontinence.
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
1. Inhaltion of tobramycin containing aerosols using the INeb® in the TBM mode is less effective as inhalation of in the TIM mode; 2. The amount of deposition is correlated to the systemic Area Under the Curve of tobramycin after inhaltion of…
Does heated oxaliplatin reduce the acute peripheral neuropathy complaints in patient with a colorectal carcinoma.
1. Currently, there are a wide variety of therapeutic techniques for specific patients and certain psychological problems. The guidelines on mental health care focus only on the specific therapy factors. In addition to these specific therapy factors…
Nowadays after every venous treatment some form of compressive treatment is prescribed. Its use has been proven for surgical interventions, but is unclear for EVLT. Patients often think of wearing of these stockings as a burden.Therefore we will…
In lungcancer bone metastases appear frequently en they are an important cause of pain. The expectation is that Bondronat® gives a fast pain reduction. In this phase II study will be examined whether this fast pain reduction indeed occurs and if…