359 resultaten
The hypothesis of the present study is to demonstrate that detection of a particular pattern (e.g., persistent vs. non-persistent) of myocardial (alpha)V(beta)3/5 expression by scintigraphy imaging at 3 and 8 weeks after MI can be used to determine…
The measurements of overnight SpO2 and/or gas mixing and/or overnight cough might be useful in CF patients aged 0-4 years old. In this age group, standard spirometry can not (yet) be performed. As a consequence, there currently are no measurements…
Lapatinib inhibits the function of Cytochrome P450 3A isoforms and P glycoprotein.
Brachytherapy is globally used as a primary treatment for prostate cancer. The advantage of brachytherapy is that the radiation dose on healthy organs can be limited. Because prostate cancer is a multifocal disease the whole prostate has to be…
Does sildenafil improve tumour perfusion?
Obesity-related factors rather than obesity itself predispose to complications in pregnancy.
It is hypothesized that residents in small scale living facilities, compared to those in regular nursing home care, have a higher quality of life and functioning. In addition, it is hypothesized that their family caregivers experience less burden…
It is generally accepted that the early-postoperative flow increase is indicative for successful maturation of an autologous arteriovenous fistula. Our hypothesis is that a patient-specific computer simulation model should be able to predict this…
The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent…
Intraneural injection of anesthetics in upper and lower extremity blocks increases the risk of neurological damage.
1.The Dutch version of the walking impairment questionnaire is a valid instrument for measuring walking disability in patients with peripheral arterial disease; 2.There is a difference between the walking ability experienced by patients on a…
Osteoporosis is common in patients with SCI and often causes fractures and is undertreated. Besides immobilization, other (endocrine) disturbances such as hypogonadism and/or growthhormone deficiency, which are seen after SCI with accompanying…
There is an increase in concentrations of cytokines IL-1alpha, IL-1RA and IL-8 (as measured using Sebutapes) in the skin of the arm in healthy volunteers after mechanical loading of the skin, compared with an control measurement.
Lacunar strokes tend to show secondary worsening of symptoms, more often than cortical strokes. This is probably due to (extreme) blood pressure falls during the night in hypertensive patient's, causing hypoperfusion of the brain.
Our hypothesis is that although treatment with etanercept improves the psoriasis and thereby the quality of lives in most people who are treated, in some people fatigue occurs as adverse event.
Preterm born infants have more gastrointestinal symptoms such as constipation.
Hypothesis in this trial is safe enhancement of the efficacy of chemoradiotherapy in resected and irresectable primary GBM patients, by using the anti-edema effect of bevacizumab and its vascular normalization response.
1. Vascular inflammation becomes activated several days to weeks before an acute coronary syndrome; 2. Biomarkers of (vascular) inflammation, endothelial activation and hypercoagulability become elevated before the event. Limited knowledge is…
Compared to a baseline period, the treatment period leads to a significant reduction in catastrophizing, fear of pain, and disability.
Hypertension causes subclinical and clinical damage in end organs. The exact manifestations of end organ damage in hypertension itself are unknown. The hypothesis is that differences in the cardiovascular risk profile in hypertensive patients are…