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We hypothesize that in patients with severe corticosteroid dependent asthma Dabigatran etexilate will: 1. Reduce airway inflammation; 2. Improve asthma control and pulmonary function; 3. Reduce hypercoagulability in the airways.
A restrictive fluid regimen is beneficial for postoperative recovey after abdominal surgery, as to hospital stay and postoperative complications.
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
We hypothesis that antiplatelet therapy adjunctive to rt-PA thrombolysis improves outcome by preventing re-occlusion in terms of three months clinical outcome.
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
Secondary cytoreductive surgery added to chemotherapy will increase progression free survival in selected patients with first platinum sensitive recurrence of ovarian cancer with a minimal negative effect on their health-related quality of life.
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…
Children with chronical abdominal pain and small intestinal bacterial overgrowth supplemented with probiotics will show less abdominal pain compared to placebo.
In this double-blind randomized controlled trial, we would like to show that a five-day treatment course with 16mg/day oral dexamethason is effective in inducing recovery from an exacerbation of MS.
Pain Rehabilitation Programs (PRP’s) are proven effective for patients with chronic musculoskeletal pain (CMP). Evidence about the relationship of dose on the effect of PRP however, is unavailable. We hypothesized that shortening PRP will not be…
It is expected that STIP shows superior efficacy in terms of faster improvement in the first 12 months of the trial and a higher recovery rate at 24 months of follow-up. In addition, it is expected that the higher direct medical costs of STIP are…
Percutaneous, ORIF and conservative treated of displaced intra-articular calcaneal fractures have a similar outcome as measured with the AOFAS (American Orthopaedic Foot and Ankle Society) score.
Combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.
Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
The aim of the study is to assess whether in women with early PPROM tocolytics improve perinatal outcome.
Ultrasonography can be used for detection of occult scaphoid fractures.
Contrast-enhanced ultrasound with microbubbles will localize the same axillary lymph node as Technetium-99m nanocolloid.
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