197 resultaten
1. Leadless Pacemaker (LP) therapy is superior to current standard-of-care (SOC) with regard to procedure-related complications in Transcatheter Aortic Valve Replacement (TAVI) patients who develop conduction abnomalies (CA). 2. LP therapy reduces…
An unsupervised proprioceptive balance board training programme that is applied after the usual care of individual athletes who have sustained an acute sports-related lateral ankle ligament injury is effective for the prevention of ankle sprain…
Tranexamic acid reduces the necessity for surgery and increases quality of life.
Evaluating the smell of e-liquids from different brands with similar flavors allows us to select the brand that most closely represents this particular flavor.
urge incontinence is caused by overactivity of the detrusor muscle of the urinary bladder. Electrical stimulation of the pelvic floor muscles can suppress detrusor overactivity. The miniaturo tm-i system is designed to deliver mild electrical…
1. The predictive biomarkers for tumor response to immuno modulating therapy will be a combination of adaptive and innate immune status per patient that will be estimated with a tumor biopsy before, 6 weeks after start treatment (optional) and at…
The effectiveness of a health game based on a Go/No-Go (GNG) paradigm compared to a GNG control game and a double control game will be tested in a Dutch sample of children between 10 and 13 years of age. It is expected that the children in the…
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Listening to music by using an audio pillow, will reduce the pain experienced during an ultrasound-guided prostate biopsy,
1)What are the important design-, usability issues and recommendations when attempting to improve a prototype smartphone application for patient-reported pain outcomes? 2) What is the difference in pain intensity self reported by the patient and the…
We hypothesise that basal ganglia are involved in sentence processing whenever a sentence structure deviates from the predicted structure and this in order to inhibit the irrelevant structure and to switch to a revision process.
Combination therapy of steroids plus MTX induces remission faster and will therefor reduce steroid toxicity and disease damage.
Preventive parenting support for parents after separation, leads to: - more knowledge about (co-)parenting strategies; - more intentions to use positive (co-)parenting strategies; - increased feelings of competence; - increased awareness on the…
The Rotterdam Daily Exercise Project leads to less overweight, improved fitness, healthier food habits and healthier exercise habits.
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
Survivors of sepsis are at high risk for the development of chronic kidney disease (CKD), cardiovascular events and mortality. Mitochondrial dysfunction, which mainly results from increased generation of free radicals, plays a key role in the…
The aim of this study is to show whether TDM leads to a lower proportion of patients with drug levels below the predefined TDM targets after 12 weeks
We hypothesize that the epigenetic changes that are related to childhood trauma provide a treatment target for succesful treatment with SAMe of persistent depression in bipolar disorder
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…