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We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
Bimanual performance is a prerequisite for the independence and participation of young children with Cerebral Palsy (CP). Home-based training programs may be a useful addition to centre-based rehabilitation programs to improve this bimanual…
We hypothesize that endoscopic combination therapy, including in- and excision of the stenotic fibrotic ring combined with steroid injections and bougie dilation, is more effective than standard repeated endoscopic bougie dilation.
- surgical treatment for CMC OA is effective in terms of pain, function and satisfaction - There is a relatively large group of patients with significant residual pain and functional impairment or deterioration of their complaints - Baseline factors…
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
No difference in range of motion at 12 months follow-up
Prevalence of PNH in selection of patients with DVT. Patients younger than 30 years of age. patients with DVT on unusual places.
1. It is common to stratify a dataset on gender and age when identifying frequent attenders within general practice. However, this could lead to an oversampling of patients with chronic diseases, e.g., cardio-vascular disease or diabetes. We…
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
Wheelchair mobility skills training and wheelchair fitness training will both increase the level of physical activity in wheelchair using children and adolescents. Wheelchair fitness training prior to wheelchair mobility skills training will show a…
VR turned out to be promising as adjunct non-pharmacological intervention during wound dressing changes. Because the evidence for VR as pain relief is limited, more high-quality studies are needed to investigate the effect of VR on procedural pain.…
Pelvic floor muscle training supported by vaginal and abdominal biofeedback, serious games and a web-portal is non-inferior to pelvic floor muscle training alone.
Physical exercise is not only beneficial for general health, but has also been shown to improve brain function (cognition) and influence brain structure (increase brain volume, especially in the hippocampus). However, the underlying neural…
We hypothesize that performing DBS under general anesthesia will (1) further improve outcome by lessening postoperative cognitive, mood and behavioral adverse effects, (2) shorten surgery time and hospital admittance, and (3) produce comparable…
We hypothesize that implantation asymmetry (IS), angular rotation (AR) and undersizing (AUI) are predictors for the occurring of subsidence. Furthermore we believe subsidence is related to decreased clinical outcomes. Presumably Total Disc…
A bounding exercise programme is effective in preventing hamstring injuries in male amateur soccer players and has a good compliance
We aim to investigate the effect of a comprehensive discharge bundle, the Transfer Intervention Procedure (TIP), on the time between discharge and the time when the medical, medication and nursing handovers are sent to the next health care provider…
Internet-based unguided self-help interventions for alcohol moderation (AM) will show favourable effectiveness compared to the control group (internet-based information brochure on alcohol moderation), 6 months post-randomisation.
Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of Paracetamol and Diclofenac and regarding the additional effect of pain medication compared with advice…