464 resultaten
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
Patients who will train with the SCRIPT-system will have similar or improved arm and hand function in comparison with the patients who receive conventional arm and hand exercises.
The aim is to investigate the effects, costs, and feasibility of an evidence-based professional-directed implementation strategy to implement the Dutch peri-operative guidelines, i.e. to achieve a higher adherence to these guidelines. It is…
Use of IBD-live for 1 year: 1. Reduces the relapse rate from 40% to 25%; 2. Increases quality of life (assessed with the IMPACT-III questionnaire).
1. Verbeteren van de overleving in vergelijking met de eerdere protocollen van de SKION, in het bijzonder ALL-9 and ALL-10. Doelstelling is om therapie te verminderen voor een deel van de patiënten (TEL/AML1, Down syndroom, geïsoleerd slechte…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
The aim of the study is to determine whether cardiac output measurements obtained using APCO are comparable with those obtained using transpulmonary (advanced FloTrac software) and intermitted bolus thermodilution cardiac output in critical ill…
Relative to the control condition of 'recall only' the experimental condition of 'recall + eye movements' will produce a reduction in both the 1) subjective vividness/emotionality of the mental image and associated recall-induced…
We hypothesize that in rheumatoid arthritis (RA) patients responding to adalimumab, with high adalimumab serum concentrations at least 28 weeks after treatment initiation: 1. Lowering the serum concentrations through dose interval prolongation will…
We hypothesize that in patients with severe corticosteroid dependent asthma Dabigatran etexilate will: 1. Reduce airway inflammation; 2. Improve asthma control and pulmonary function; 3. Reduce hypercoagulability in the airways.
The hypothesis is that an accurate history, conventional markers of sensitization, IgE antibodies in the serum and positive SPT, and more advanced techniques (MRAs and component resolved diagnosis (CRD)) might predict clinical allergy to cashew nuts…
The quality of human milk shows an association with the women's diet and lifestyle.
Dietary inorganic nitrate supplementation will decrease O2 cost of exercise in patients with mitochondrial myopathy.
Compared to a control group, the mindfulness group intervention is expected to result in: 1. A decrease in symptoms of psychological distress; 2. An increase in quality of life; 3. An increase in heart rate variability; 4. A decrease in blood…
Falls are common in elderly and often result in adverse consequences. The effectiveness of C-Mill training, i.e. treadmill walking with a specific emphasis on functional walking ability via constant and irregular gait modulations, obstacle crossing…
Phase I: To investigate whether it is feasible to organise an international multi-centre pragmatic trial to study the value of individualised homeopathic add-on treatment using a semi-standardised algorithm in women with premenstrual disorders,…
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
HCQ causes both autophagy inhibition and chromatin modification, thereby (re)sensitizing tumor cells to EGFR TKIs, hypothetically increasing response rates after one week.
There will be a relation between the level lidocaine in newborn, the level in mother and drug-delivery interval.
The primary objective of this study is to evaluate the web-based intervention 'Leven met Pijn' in comparison to a minimal intervention condition and a waiting list control condition in terms of a decrease in pain interference in daily life…