103 resultaten
Frequently people experience nausea and vomiting following surgery. There are several pharmacologic interventions possible; there is no rational evidence-based approach available. In this study the current therapy regaring PONV and its efficacy in…
A patient centred or a porfessional directed intervention to improve adherence to diabetes guidelines in hospitals are more (cost) effective compared to usual care.
We hypothesize that TVT-O and TVT-S are equally effective in the management of stress-incontinence. We hypothesize that there are differences in morbidity and post-operative recovery between both procedures as TVT-S it is a less invasive technique.
1. Both paroxetine and cognitive behavioural therapy (CBT) are effective in the treatment of late-life panic disorder; 2. Differences in efficacy between paroxetine and CBT are small.
Anastomotic strictures are common after esophageal resection. These strictures often need multiple dilation procedures with Savary bougies, and some even fail despite many dilations. Based on the literature and our pilot study of electrocautery…
1. Adherence to guidelines/protocols is unsatisfactory; 2. No regimen is superior in the proportion of patients with minimal or no impact of emesis on daily living as measured using the Functional Living Index-Emesis questionnaire.
Diabetes care can be improved by task dellegation to a practice nurse supported by computerised decision support and benchmarking.
We tested, in a randomized, double-blind, placebo-controlled trial, the effects of duloxetine on pain relief, tolerability, health status, and quality of life in patients with central neuropathic pain.
A systematic screening and a lifestyle-intervention for pre-diabetes targeted at the Hindustani Surinamese population will prevent or postpone the onset of diabetes mellitus type 2.
Sympatho-adrenergic and hypercoagulable activity are enhanced in patients with chronic heart failure, partially mediated by common functional beta2-adrenergic receptor polymorphisms. Non-selective beta-blockers down regulate sympathetic activation…
Several reports have indicated that the chemokine receptor CCR5 and its ligands, escpecially CCL5 (formerly known as RANTES), may play a role in the pathogenesis of psoriasis. CCR5 targeted treatment could therefore be a therapeutic option for…
To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.
In the present placebo controlled study we will investigate the influence of valence on attention when viewing visual erotic stimuli. Especially when under the treatment condition of testosterone with sildenafil. In addition, we will investigate the…
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SLE patients show a decreased humoral immune response to influenza vaccination, as compared to healthy controls. Furthermore the use of immunosuppressives is of influence on vaccination immunogenicity, it has been demonstrated that the use of drugs…
Elective laparoscopic appendectomy is a usefull procedure in patients with chronic or recurrent right lower abdominal pain.
Improving the rate stage III/IV pressure ulcers heal through nutritional support.
In each stratum of probability there is a clinically and statistacally significant difference in the functional ability and disease activity score over time (area under the curve) and progression of radiological joint damage after 1 year of follow-…
Current clinical practice varies widely, especially for infants with 'moderate' hypoglycemia, due to lack of methodological sound studies. This leads to both over- and under-treatment of hypoglycemic infants. This study-protocol is…
The aim of the study is to determine the dose-limiting toxicity (DLT) and maximum-tolerated dose (MTD) of irinotecan and cisplatin with concurrent thoracic radiotherapy in patients with LD-SCLC as a once every three weeks schedule.