371 resultaten
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
1. Measure DNIC and offset analgesia in neuropathic pain patients; 2. Compare DNIC and offset analgesia in chronic pain patients with DNIC and offset analgesia in healthy volunteers; 3. Assess the effect of oral tapentadol on DNIC and offset…
Recent research shows that obesity is associated with changed bowel flora composition with a relative abundance of the two dominant bacterial divisions, the Bacteroidetes and the Firmicutes. Interestingly, this specific bacteria associated condition…
Our main objective is to investigate whether an augmented CBT leads to the reduction of depression and anxiety symptoms in stroke patients. We will compare the outcomes of this experimental treatment with a control intervention (i.e., computerized…
1. Volume intervention by a diuretic and moderate sodium diet potentiates the antiproteinuric effects of aliskiren in patients with residual albuminuria during conventional RAAS-blockade; 2. Aliskiren neutralizes the reactive rise in plasma renin…
1. Assessment of safety of seasonal and pandemic inactivated whole virion influenza vaccines; 2. Assessment of immunogenicity of the whole virion vaccines; 3. Comparison of the safety profile of the whole virion vaccines with a split virion vaccine.
Remote ischemic preconditioning (RIPC) has been shown to attenuate myocardial damage in cardiac surgery. We hypthesize that RIPC induced cardioprotection is associated with an increased amount of mitochondrial hexokinase.
Oxytocin administration leads to stronger empathic reponses and faster emotional processing.
1. To investigate the efficacy of Cogmed working memory training in reducing behavioral symptoms in children with neuropsychiatric disorders and borderline intellectual functioning; 2. To investigate whether WM training improves neurocognitive…
The primary objective of this study is to test the hypothesis that risperidone given orally in a dose of 0.25 – 3.0 mg/d depending on body weight (eq. to approximately 0.01 – 0.04 mg/kg/d) for 12 weeks is superior to placebo in reducing…
An adaptive EF training will improve EF performance and behavior, complex reasoning, ADHD characteristics, general problem behavior and motivation compared to a non-adaptive training condition.
This study evaluates the beneficial effects of exercise training with or without oral anti-diabetic medication in patients with coronary artery disease (CAD): PCI or CABG in stable CAD, or post STEMI and post non-STEMI patients who have pre-diabetes…
We hypothesize that addition of low-dose haloperidol prophylaxis (1.0mg twice-daily) on top of the existing standard of care reduces in-hospital delirium incidence, severity and duration in a general patient population, age 70 years or over, who are…
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
Acetaminophen is effective in treating self-reported sleep problems, in particular insomnia.
Intravenously administered rhAPC has protective effects on HDM-LPS induced allergic lung inflammation.
In the present proposal we aim to study whether the intrauterine application of hyaloronic acid (Hyalobarrier ® Gel Endo) immediately after curettage, in patients with a recurrent curettage reduces the incidence and severity (ESGE score/…
Incorporation of vitamin E to a polyethylene acetabular cup gives less wear at 10 years compared to cross-linked polyethylene without vitamin E.
Determine safety and kinetics of IQNLF in humans.
Administration of MPH during brain development, but not in adulthood, results in an altered outgrowth of the dopaminergic system. This long-lasting disturbance of the dopaminergic system may result in behavioral abnormalities, such as anxiety and…