574 resultaten
We hypothesize that in critically ill patients, measuring the anti-factor-Xa randomly in a 3 to 5 hours timeframe, may introduce a significant variation in the measured anti-factor-Xa and can seriously underestimate the real peak anti-factor-Xa.
A 12 weekly computer-tailored coaching program reduces sedentary behavior. Perceived bodily pain, mental health, vitality, stress, and performance are expected to lower by the means of reduced sitting time.
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Exploratory study investigating the efficacy of the currently recommended dosing regimen of ciprofloxacin prophylaxis in patients treated for haematological malignancies.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
In validating the TICS and MoCA questionnaires against NPT, we hope to find a patient friendly and easy to use screening aid for preoperative evaluation clinics.
(1) The stand-alone treatment of sleep problems will have a clinically significant effect on the reduction of ADHD symptoms in adults with ADHD. (2) The concurrent treatment of sleep problems and usual care is more effective than usual care to treat…
It is an observational study, no null hypothesis has been formulated. The purpose of StEM is to understand the expectations, needs, experiences, choices and decisions of pregnant women and women who recently gave birth in the Netherlands, recording…
High-resolution ultrasound (HRUS) is a quick and cost-effective technique to study the morphology of peripheral nerves. Sonographic characteristics of plexiform neurofibromas and MPNST have been described in the literature. Recently, a pilot study…
Awake craniotomy improves safety and efficacy during surgery for glioblastoma in eloquent areas
We hypothosize that audio-visual immersion by using high-quality video glasses with surround sound headphones can reduce pain and anxiety scores. Furthermore, we anticipate that patient satisfaction in these patients will increase.
It is expected that fatigue will decrease and quality of life will increase after participating in the RE-SAB program
We hypothesize that DVT can be safely ruled out by the LEFt rule in combination with the D-dimer test in 5-10% of pregnant women, and that a normal MRDTI safely rules out isolated pelvic vein thrombosis. We hypothesize that 7-10% of performed MRDTI’…
Individual-directed resilience training can reduce chronic stress and prevent burnout among students
For this feasibility study, no hypothesis have been made.
Intra uterine exposure to anti-TNFα inhibitors influences the normal development of the immune system, leading to immunodeficiency and immune dysregulation, with the potential to cause short term and long-term morbidity. TNFα plays an important role…
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.
The hypothesis is that twins discordant for pregnancy complications display a distinct epigenetic signature in MSCs. This signature contributes to cellular metabolic alterations and is associated with future cardiovascular and neurodevelopmental…
This project aims to investigate the feasibility and oncological safety of eFTR as minimal invasive completion treatment following previous incomplete endoscopic resection of low-risk T1 CRC.