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Because little is known on the effective and safe dosage of propofol when used for control of intracranial pressure in head-injured patients, propofol blood and cerebrospinal fluid concentrations and pharmacodynamics are characterized in order to…
Cross-transmission of antibiotic-resistant pathogens can be prevented by using closed suction systems (CSS) instead of open suction systems (OSS) in mechanically ventilated ICU patients.
1. The level of suicide ideation is correlated with al ow level of positive future expectencies 2. Our future oriented training will help people to predict a more positive future 3. And this will lead to less suicide ideation
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
1. The intervention group will have a lower BMI/waist circumference, compared to the control group at follow-up; 2. The intervention group will have more favourable outcomes on the targeted behaviours, compared to the control group at follow-up; 3.…
We hypothesized that forming implementation intentions may increase levels of physical activity.
1a. Changes in outcome measures of anxiety can be partly explained by changes in self-reported thougths; 1b. Changes in outcome measures of anxiety can be partly explained by changes in selective attention and by changes in fear relevant cognitive…
A more gradual training program for novice runners, will result in a reduction of running related injuries in novice runners.
Rituximab treatment leads to a decrease in synovial B cells. The clinical response is related to the decrease in synovial B cell numbers.
The primary aim of the study is: 1. To assess the role of an early intensification of two "AML" induction blocks versus protocol Ib directly after induction, in a randomized way in MR and HR patients. Secondary aims are: 2. To assess the…
(stress-sensitive) Patients with functional dyspepsia have a change in the dopaminergic system, through chronic stress, what leads to visceral hypersensitivity and therefore dyspeptic symptoms.
Botulinum toxin type A injection of the prostate causes relaxation and cellular apoptosis and by this way will relieve lower urinary tract symptoms in patients with benign prostatic hyperplasia.
The promotion of safe sports participation proves effective in a physical education setting, resulting in a reduction of lower extremity injuries in children.
In this epidemiologic study a cohort of patients with MFT transferred and/or referred to the National Hospital of Odonto-Stomatology Ho Chi Minh City (NHOS-HCMC), Vietnam, was analyzed following the MFISS and FISS protocol. This study will give a…
A health education program for both patients and general practitioners will change behaviour by 15%.
Goal: 1. Defining normal electophysiologic matarution in premature infants by quantitative analysing techniques; 2. Identifying circumstances that disturb normal electrophysiologic maturation.
It is hypothesized that long term disabled persons who participate in the MDR program will return to work and have less mental and/or physical limitations to prevent te pre-disability income. Furthermore an explorative study into the process…
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
Hypothesis 1: the Groningen ULR and the Provox®2 are the same in terms of the replacement method, the burden on the patient and the convenience of the replacement and of the resistance during phonation. Hypothesis 2: the Groningen ULR has a longer…
Based on studies in other types of cancer in humans where beneficial effects were obtained, and based on our pre-clinical data in a mouse model for malignant mesothelioma (MM), it now seems feasible and warranted to introduce dendritic cell (DC)-…