1636 resultaten
To investigate the safety, tolerability and pharmacokinetics after multiple daily doses of YTX-7739
Cylindrical shaped interdental brushes removes more dental plaque at the approximal surfaces than conical shaped.
Children with chronical abdominal pain and small intestinal bacterial overgrowth supplemented with probiotics will show less abdominal pain compared to placebo.
We expect that OT administration in PTSD patients and controls will dampen amygdala activity and increase reward sensitivity. We hypothesize to see a group by treatment interaction effect, such that the magnitude of the neural effects of OT…
The overall survival in the arm treated without chemotherapy (TNM-stage II or III tumours) is expected to be approximately 60%. Assuming an improvement in overall survival from 60% to 70% in the arm treated with chemotherapy (TNM-stage II or III…
Type of feedback will have an influence on learning to control grip force.
Surgery is the standard therapy for esophageal cancer. However, 30% of the resections are irradical. It is thought that preceding chemoradiotherapy will improve the surgery results.
medication reconciliation by pharmacists decreases the amount of medication transfer errors in patients admitted to the intensive care
Early introduction of an amino-acid based formula (AAF; Neocate® Syneo) in infants with non-IgE mediated cow's milk allergy (CMA) accelerates resolution of clinical symptoms compared to a whey based extensively hydrolyzed formula (eHF; Nutrilon…
Previous studies have shown that the half life of adalimumab increases to up to 21 days, after several doses have been administered. As such it seems possible to increase the dosing interval from 14 days to 21 days, in patients IBD in long term…
Use of the GEM microvascular anastomotic coupler is feasible in coronary artery bypass procedures with the extended radial artery technique and the coupler anastomoses is patent after 3 months.
We hypothesise the following; 1. Lowering the incidence of contrast induced nephropathy is possible when the diuresis is increased up to >300 ml/hour during the intervention (PTA) and is continued up to 4hours after the revascularizing…
In this study the relationship of OSAS with cognitive and functional status, and the effect of treatment with CPAP on outcomes of rehabilitation in stroke patients will be investigated. The main research questions are: 1. Is there a relationship…
To assess the change in arterial wall inflammation, measured with 18F-FDG PET/CT, in patients with increased CV-risk and statin intolerance due to statin-associated muscle symptoms after PCSK9 inhibition
We hypothesized that, in high PD-L1 expressing patients with high tumor burden, the combination of pembrolizumab with platinum-based chemotherapy will result in a higher tumor response, and possibly in a better progression free and overall survival…