2288 resultaten
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
1. Prosthetic valve characteristics (type; location; size resulting in the presence/absence of PPM) are related to functional outcome and quality of life; 2. The incidence/spectrum of prosthetic valve-related complications in adults with CHD differs…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
Objectives are: 1) To determine the feasibility of an OA educational self-management course, by assessing the appreciation of health care providers and participants, participation and barriers and facilitators to participation. 2) To determine…
In the present study we will investigate the pharmacokinetic profile of three doses of sublingual testosterone, and measure subjective and physiological measures of sexual functioning in healty premenopausal women. The lowest effective dose of…
AN-PEP helps to digest gluten in vivo.
We expect that STRAVA users who will stop with using the self-tracker will experience body empowerment, while people who are using no self-tracker and will start using STRAVA will experience body alienation.
HCQ causes both autophagy inhibition and chromatin modification, thereby (re)sensitizing tumor cells to EGFR TKIs, hypothetically increasing response rates after one week.
We hypothesize that in current dermatological practice, there is a undisclosed burden of psoriatic arthritis in psoriasis patients. We wish to discover the prevalence of known and unknown arthritis in these patients, and find clinical and…
The objectives are firstly that the Tackling Teenage training increases knowledge, skills and confidence of young people with autism spectrum problems (ASP) , and that inappropriate sexual behavior decreases and secondly that the (sexual)…
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
Patients who undergo aortoiliac surgery for occlusive disease have higher rates of SSI compared to aneurysmal disease.
To identify (both primary and acquired) resistance mechanisms to chemo-immunotherapy (obtained by less invasive procedures (NGS on ctDNA in blood & urine, exhaled breath or microbioma in stools alone or in combination)) and provide new…
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
the Aeonose is able to discriminate between patients with Barrett’s esophagus versus patients without a diagnosis of Barrett’s esophagus.
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
Higher concentration nintedanib in normal lung tissue compared to fibrotic lung tissue.
A low peak E2 during COS is considered to be safer than a high peak E2 in women with breast cancer