183 resultaten
Gut-homing lymphocytes play a role in the development and maintainence of perianal fistula in Crohn's disease patients.
Being diagnosed with prostate cancer impacts patients quality of life. Besides choosing a treatment strategy that suits patients' values and preferences, they may look for subsequent strategies to cope with their disease. Dietary changes may…
We hypothesize that ESD will be associated with longer procedure times but lower costs. For lesions that prove to be benign, we hypothesize that ESD will lead to a higher number of R0 resections and lower recurrence rates, particularly for lesions…
A family involvement program will reduce the number of unplanned readmissions in adult patients undergoing major abdominal surgery.
Effectiveness of Moving Stories, a game-based school program aimed at depression literacy and stigma
Our first hypothesis is that adolescents who’ve participated in the Moving Stories program will have better mental health literacy and fewer stigmas regarding depression than adolescents who have not participated, both at posttest and at three- and…
We expect that treatment with azelastine/fluticasone propionate will decrease exercise tolerance limitation and will improve quality of life.
The main objective of this study is to evaluate the efficacy of the blended eHealth cognitive behavioural intervention as an additional treatment to treat insomnia (e-CBT-I) in people with acquired brain injury. The main research questions are: 1…
Performance of the Aeonose™ as a diagnostic tool to detect lung cancer: an external validation study
Primary Objective: To investigate the diagnostic performance of the Aeonose™ to distinguish breath of subjects suspected for lung cancer who are truly diagnosed with lung cancer from subjects suspected for lung cancer in which this diagnosis is…
The use of higher field strength MRI-scanners will improve the detection of (small) structural brain lesions in patients with focal drug-resistant epilepsy, potentially resulting in better seizure outcome after resective epilepsy surgery.
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
We hypothesize that socioeconomic inequalities in diet quality are partly explained by differential dietary costs.
As plasma glucose during surgery increases, because of the surgical stress response and accompanied insulin resistance, this will lead to an acute supply-demand mismatch and excess of glucose in the brain. We hypothesize that this leads to…
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
By giving high dose, radical, radiotherapy to patients with recurrent lung cancer, the overall survival can be prolonged and local control rate can be increased which can be done with acceptable toxicity for the irradiated normal tissues.
The use of structural biomarkers (e.g. fundus autofluorescence imaging, optical coherence tomography or a combination thereof) may show a much more gradual progression that is indicative of functional vision loss at a later stage.
It is hypothesized that this personally tailored physical activity program (I’M FINE intervention) will be more effective in improving physical fitness and enhance daily activity in individuals with slowly progressive neuromuscular diseases (NMD)…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…