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We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Freezing of gait (FOG) is a particularly disturbing and potentially harmful symptom occurring in a majority of people with Parkinson's Disease (PD) over the course of disease. External cues, such as a metronome or bars on the floor, aid in…
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
H0= Postprandial muscle protein synthesis rates do not differ between the 2 intervention groups (P>0.05) H1= Postprandial muscle protein synthesis rates differ between the 2 intervention groups (P<0.05)
Mediastinal staging of NSCLC by EBUS/EUS-B with and without additional cervical mediastinoscopy are both effective diagnostic strategies for assessment of mediastinal lymph node metastases. However, omitting mediastinoscopy comprises no extra…
In pregnancies complicated by late PPROM immediate delivery might lead to better long-term outcome.
The primary objective of this study is to evaluate changes in oral health during a 4-month naval mission and once one month thereafter.
to assess the detection rate and accuracy of 18 F-FDHT PET/CT and compare to current standard restaging modalities.
Class III corticosteroid is more effective than a class I corticosteroid for treating a moderate flare-up of atopic dermatis in children.
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
The effects of a brief compassion induction exercise will be compared to the effects of a neutral exercise. We hypothesize that a brief compassion induction in a sample of patients with PD will facilitate the choice of more adaptive emotion…
We expect to detect testosterone effects on response to exposure in terms of subjective anxiety and self reported social anxiety symptoms. Additionally we expect testosterone effects on implicit avoidance tendencies. Lastly, Personality traits,…
The hypothesis of this trial is that the implementation of a best practice algorithm for postoperative care focusing on early detection and step-up management of postoperative pancreatic fistula results in a lower rate of major complications and…
IgG4-associated cholangitis mimicks perihilar cholangiocarcinoma, resulying in patients being resected for benign disease