268 resultaten
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.
In the present study we will investigate the pharmacokinetic profile of three doses of sublingual testosterone, and measure subjective and physiological measures of sexual functioning in healty premenopausal women. The lowest effective dose of…
We expect that STRAVA users who will stop with using the self-tracker will experience body empowerment, while people who are using no self-tracker and will start using STRAVA will experience body alienation.
To explore, whether markers of mitochondrial dysfunction measured in isolated PBMCs or immune cell subpopulations differ between subjects with mitochondrial disorders and cardiomyopathy and healthy volunteers.
The addition of the EGFR monoclonal antibody Cetuximab to standaard concurrent chemoradiotherapy improves the outcome of treatment of locally advanced non-small lung carcinoma.
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in children's on-task behavior; 3. An increased teacher…
The goal of this trial is to investigate whether (and at which dose or ratio) CBD has a modulating effect on the psychotropic effects of THC by comparing the effects of THC to the combination of THC with CBD in a range of ratios. Simultaneously,…
Effectivity of information transfer between ambulance personnel and hospital staff (% content using SBAR system) Efficiency of information transfer between ambulance personnel and hospital staff (time)
To study's primary objective is to establish the effectiveness of a low-threshold guided self-help intervention targeted at improving one's self image in people with anxiety and/or depressive symptoms and low self esteem. We expect to find…
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
An ICT-supported, integrated, multidisciplinary treatment of COPD in primary care compared to usual care in primary care practices will improve the quality of life of COPD patients at an acceptable level of cost-effectiveness.
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
It is expected that the Maximum voluntary contraction (MVC) method is preferered over the rest EMG method. Because, stroke patients expierence a unvoluntary contractions, spasticity etc. which influences the rest EMG.
Partners participating in the HmT-online course will show improvement on outcome measures post-treatment and at follow-up compared with pre-treatment scores.
In patients with specific mutations in lipid metabolism we will find retinal abnormalities that can be identified as (a precursor of) age-related macular degeneration.
To gain more insight into the pathogenetic processes involved in Sjogrens Syndrome(SS) bij analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and…