126 resultaten
The null hypothesis of the primary outcome measure is that there will be no significant differences in DASH scores 6 months after surgery between patients who underwent plate fixation or intramedullary fixation with a TEN. The alternate hypothesis…
To study's primary objective is to establish the effectiveness of a low-threshold guided self-help intervention targeted at improving one's self image in people with anxiety and/or depressive symptoms and low self esteem. We expect to find…
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
The purpose of this study is to demonstrate the added value of using 'LMA-S in the ambulance with CPR in the Netherlands indigent patients. The hypothesis is that the value of using the LMA-S is located in the safety and speed of placing the…
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
Tropicamide is less effective in inhibiting accommodation and has a small window of maximum activity. Cyclopentolate is more effective but in darker pigmented subjects a significant residual accommodation can be present. Children often show…
1. Cooling to 34, 34.5 or 35°C by means of a surface cooling device, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours in awake patients on a stroke unit is safe; 2. In awake patients with ischaemic…
Primary objective: Does a 30-minute episode of helium breathing in humans decrease the amount of pro-inflammatory cytokines and chemokines produced in whole blood after immunostimulation ex vivo?
After receiving PST, stroke patients will have a more effective coping style followed by a better quality of life.
ICG alone without being absorbed to albumin can be used for near-infrared fluorescence SLNB in breast cancer patients.
A four day adminstration of N-acetylcysteine (3600 mg/day) will reduce craving, withdrawal symptoms and the bias towards nicotine related cues compared to a four day administration of placebo in nicotine dependent subjects.
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.
Patients undergoing a minimally invasive oesophagectomy have fewer morbidity, a shorter duration of the intensive care unit (ICU) admission and a better quality of life than following the traditional approach.
1. The treatment group will increase their Theory of Mind skills in comparison to the waitlist control group; 2. The conceptual skills will improve at a higher rate than the practical skills.
We hypothesize that there is a disturbed amino acids profile in the cardiac surgical patient and that nutrition during surgery will normalize this profile with a subsequent improvement in cardiomyocytes functioning by histology, and in cardiac…
The percutaneous and lipofilling technique has a shorter convalescence.