136 resultaten
1. A treatment strategy aimed at well controlled asthma is more (cost-)effective as compared to a treatment strategy aimed at achieving partly controlled asthma; 2. A treatment strategy aimed at well controlled asthma is (cost-)effective when the…
Shoulder pain is related to somatosensory and nociceptive changes in the acute phase after stroke. These changes may indicate the involvement of specific mechanisms (nociceptive, neuropathic) of post-stroke shoulder pain. Changes may either precede…
Modifications in surgical technique and rehabiliation procedures will improve survival of the Oxford UKA.
We hypothesize that allergic asthmatics are less capable in resolving inflammatory cells after viral airway infection as a consequences of impaired expression of indoleamine 2,3-dioxygenase.
Dementelcoach: effect of telephone coaching on caregives of community dwelling people with dementia.
With taking care of community dwelling people with dementia the responsibility ends up mostly with one primary caregiver. The caregiving is a heavy burden and results in stress. Caregivers have a life expectancy of 6 to 7 years les than people who…
The investigational formulae are equivalent to the currently marketed control formula with regard to weight gain of healthy full-term infants during first 16 weeks of life.
The hypothesis is that the patients who were counselled according to the intervention will return-to-work earlier and will have a better quality of life than patients who were counselled according to usual care.
H0= Saline is inferior to sodium bicarbonate for the prevention of contrast induced nephropathy in patients undergoing computed tomography after intravenous contrast administration. H1= Saline is noninferior to sodium bicarbonate for the prevention…
Better guided resection of brain areas that are, regarding network characteristics, important for seizure onset and propagation may result in improved clinical outcome. However, before such guidance is possible, more insight into the effects of…
The aim of this protocol is twofold. 1. Firstly, we aim to combine the new response monitoring method (PET imaging) with the present technique (dynamic CE-MRI imaging) in order to discriminate between favourable and unfavourable response of the…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
In the elderly patient with a proximal intracapsular femoral fracture a hydroxy-apatite coated uncemented hemi-arthroplasty will lead to a lower mortality rate and less servere complications compared to a cemented hemi-arthroplasty.
The purpose of the present study is to obtain a pharmacokinetic profile of ropivacaine in serum with epinephrine, and of ropivacaine in serum without epinephrine, used for high dosed combined femoral and sciatic nerve block in lower extremity…
MRI leads to higher prostate cancer detection: MR guided prostate biopsy and MR-ULtrasound Fusion Guided prostate biopsy will yield higher detection rates in comparison to Transrectal Ultrasound guided prostate biopsy.
Detection of chronic pain in adolescents by self-report combined with advice from a school nurse will be efficient and effective.
Hypothesis: the working mechanims of metformin can be partly explained by its effect on the composition of the gut microbiota, with changes in inretin secretion and inflammatory pathways as secondary effects.