121 resultaten
Does suppletion of vitamine D3 (cholecalciferol) have an effect on the systolic blood pressure in hypertensive, vitamin D insufficient patients? 1. H0 hypothesis: there is no effect on the systolic blood pressure; 2. H1 hypothesis: the systolic…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
Een klinisch behandelprogramma met een opnameduur van acht weken gevolgd door een intensief vervolgprogramma voor kinderen (8-19 jr.) met ernstige obesitas is kosten effectiever dan een klinische interventie met een opnameduur van zes maanden en…
An activity stimulation program improves mobility performance and fitness in children with cerebral palsy.
Early treatment of a clinical varicocele in subfertile men results in more spontaneaous pregnancies as compared to no treatment.
By detection of disease specific deviations in emotion processing in unipolar vs bipolar patients, affective neuropsychological tests and fMRI could be used to discriminate between both affective disorders.
Use of the Online Exercise Coach, an online tailored exercise program, will enhance compliance with a prescribed exercise program.
There are many avoidable deaths in hospitals because the care team is not well attuned. Training in emergency situations is generally followed on an individual basis. In practice, however, hospital patients are treated by a team composed of various…
That clozapine treatment compared to risperidone treatment is associated with a significant reduction in subjective craving and in a lower activity of the different functional craving pathways and their associated brain activity patterns.
Eating rate may be related to overweight. Due to a high eating rate, there may not be sufficient time to develop appropriate feelings of satiety, leading to overconsumption. We hypothesise that when eating rate is high, the ad libitum food intake is…
We expect a decrease in the expected satiating capacity of the test food after repeated exposure to the low-energy-dense version of the soup and an increase in expected satiation after the repeated consumption of the high-energy-dense soup.
The aim of this protocol is twofold. 1. Firstly, we aim to combine the new response monitoring method (PET imaging) with the present technique (dynamic CE-MRI imaging) in order to discriminate between favourable and unfavourable response of the…
Is docetaxel weekly as effective and less toxic than the same dose given 3-weekly.
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
Inspiratory Muscle Training during primary rehabilitation will improve respiratory function in Spinal Cord Injury. Respiratory Muscle Training will decrease the risk for long-term respiratory symptoms and complications in persons with spinal cord…
As the anterolateral approach is also a routine procedure, and to test how minimally invasive MIS is, we hypothesized that patients treated with a THA using a posterolateral or anterolateral MIS would experience superior clinical results compared…