300 resultaten
A 10% point difference between the intervention group and control group in IDM is expected. The sample size calculation is based on a worst-case scenario with regard to precision. For a binomial distribution, the widest distribution and thus largest…
The hypothesis is that patients with low anti-TNF drug levels have a higher risk of loss-of-response to anti-TNF drugs compared to patients with high anti-TNF drug levels.
We hypothesize that an evidence based diagnostic algorithm, using fewer and preferably the least invasive diagnostic modalities can approach the accuracy of the complete panel of diagnostic tests.
Nonsimultaneous current steered pulse trains will lead to a single pitch percept whilst reducing the amount of current in comparison to conventional monopolar stimulation
We hypothesize that medical nutrition (PN and EN) compared with no medical nutrition (only oral nutrition) will be associated with better maintenance of nutritional status (fat- and fat free (muscle) mass and body weight), functional capacity,…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
There is no relationship between the duration of the procedure under PSA and the incidence of atelectasis and/or respiratory symptoms.
We expect that planned visits at the outpatient clinic are unnecessary due to low percentage of treatment changes. Furthermore, we expect that treatment changes will appear at unplanned visits.
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
The primary objective is to investigate the feasibility of using intra-arterial ICG preoperatively to allow for liver segment visualization during anatomical liver resection.
We hypothesize that motivational and behavioral characteristics of eating behavior, in addition to genetic and environmental factors play a major role in the development of obesity. We aim to identify obesity subtypes based on these factors.
There is no difference in radiographic parameters of immediate loading and delayed loading of single posterior tooth implants in healed sites.
The objective is to identify a formulation of ModraCape001 that will release capecitabine in vivo over a time-period of about 18 hours. We hypothesize that prolonged exposure, without a high peak exposure to capecitabine, improves the benefit/risk…
We hypothesize that home-based hypnotherapy by self-exercises is more effective in obtaining adequate relief of abdominal pain and discomfort than care as usual of General Practitioners (GPs). We expect that by using the hypnotherapy self-exercises…
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
The effectiveness of an indicated indicated depression and anxiety prevention program ('Een Sprong Vooruit') will be tested in a Dutch sample of adolescents (aged 11-15) with high familial risk. It is expected that the adolescents who…