106 resultaten
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
It is expected that the Maximum voluntary contraction (MVC) method is preferered over the rest EMG method. Because, stroke patients expierence a unvoluntary contractions, spasticity etc. which influences the rest EMG.
In patients with specific mutations in lipid metabolism we will find retinal abnormalities that can be identified as (a precursor of) age-related macular degeneration.
We aim to investigate whether a preoperative fasting diet reduced postoperative fatigue at 4 weeks after living donor nephrectomy in adult patients
Survival of patients treated with hepatic arterial infusion pump chemotherapy will be superior to that of a historical cohort with similar patient characteristics
The overall aim of this proposed study is to gain insight into the target attainment of the administered antibiotics during the two-stage arthroplasty exchange, in order to determine the efficacy in relation to the minimal inhibitory concentration (…
Plasma presepsin level can differentiate between bacterial and viral infections in young infants with fever of unknown origin
Investigate the influence on the hard and soft tissues of immediate placement of a single implant in an extraction socket in the anterior maxilla. Null hypothesis: is that there are no differences in the hard and soft tissues and aesthetic outcome
A drop-out rate of 50% at 1 year follow up is anticipated.
We hypothesise that HCP provides reproducible and accurate measurements of LV volume changes during different CRT pacing settings which are comparable with invasive conductance catheter measurements.
Powerspiral enteroscopy provides an effective endoscopic procedure. Total small-bowel enteroscopy can be achieved, in one or two sessions, even in the presence of altered gastro-intestinal anatomy. It provides a great reduction of the enteroscopy…
Our hypothesis is that the efficacy of FMT in patients with active UC can be increased by: 1. Pretreatment with budesonide in patients with active UC, which may reduce inflammation prior to infusion of the donor feces solution. This reduced…
No hypothesis due to the explorative character of the study
Spinal anesthesia is a superior anesthesia technique for spinal cord stimulation procedures
QoL, CE and functional outcomes differ significantly between L-TME, R-TME and TaTME.
Primary • To evaluate the pharmacokinetics of oxybutynin and its main hepatic metabolite N-desethyloxybutynin after pulsed intra-vaginal delivery of a single dose of oxybutynin Secondary • To assess the safety and tolerability of the intra-vaginal…
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
Two doses of the Coronavirus virus-like particle subunit vaccine ABNCoV2 in SARS-CoV-2-naïve healthy adults is safe and well tolerated.