13 resultaten
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
Leflunomide is able to reduce the relapses, the glucocorticoid use and the adverse events associated with glucocorticoid s use in PMR patients.
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
Deep brain stimulation (DBS) targeted at the ventral anterior limb of the internal capsule (vALIC) is an effective treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, effective DBS for these patients requires relative…
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
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Compared to placebo treatment with low dose amitriptyline or mirtazapine during 16 weeks will improve subjective insomnia in insomnia disorder patients in general practice.
The ingestion of free amino acids will result in higher plasma amino acid concentrations, resulting in enhanced muscle protein synthesis rates when compared with the ingestion of milk.
We expect that treatment with azelastine/fluticasone propionate will decrease exercise tolerance limitation and will improve quality of life.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status.
Failure of discontinuation of off-label antipsychotics in people with intellectual disabilities is the result of (1) subjective interpretation of behavior by caregivers, influenced by fear of worsening of behavior after drug reduction, (2) a…
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.