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A 10% point difference between the intervention group and control group in IDM is expected. The sample size calculation is based on a worst-case scenario with regard to precision. For a binomial distribution, the widest distribution and thus largest…
We hypothesize that an evidence based diagnostic algorithm, using fewer and preferably the least invasive diagnostic modalities can approach the accuracy of the complete panel of diagnostic tests.
Nonsimultaneous current steered pulse trains will lead to a single pitch percept whilst reducing the amount of current in comparison to conventional monopolar stimulation
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
There is no relationship between the duration of the procedure under PSA and the incidence of atelectasis and/or respiratory symptoms.
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
The overall aim of this RCT is to examine whether an individual music intervention can improve the challenging behavior, quality of life, emotional wellbeing and EF of adults with a mild to moderate ID.
We hypothesize that repeated spot urine sampling is non-inferior to a single 24-hour urine collection to estimate 24-hour dietary sodium and potassium intake.
-The combination of center-based CR and a home-based exercise training program will lead to a greater increase in physical activity levels compared to standard care. -Continuation of home-based exercise during a three-month follow-up will lead to…
We aim to evaluate the efficacy of the `OncoSTRIP', a standardized polypharmacy assessment method, in a group of elderly patients with cancer on medication use satisfaction by using the 'Treatment Satisfaction Questionnaire for Medication…
Breast-related Quality of Life (QoL) measured by the BREAST-Q questionnaire will significantly increase after breast reconstruction with autologous fat transfer.
Ayahuasca significantly modulates high-level network functional connectivity and neurometabolite concentrations when compared to baseline.
Patients with a discrepancy between between painful-to-swollen joints have a lower score on pain sensitivity measurements (PPT, EPT and NDT) and a higher score on questionnaires (CSI, GPQ, SFD-36 and PCS).
The prevalence of HIV and STDs (Hepatitis B/C/ Syphilis/ Chlamydia/ Gonorrhea) in the adult transgender population in the Netherlands is lower than the global reported prevalence of these diseases.
Early post-operative mortality is particularly high, with reported 30-day mortality rates of 7.5 - 13.3%. Up to 5% of the hip fracture surgeries is performed in patients with a high death within 30-days after surgery. If the preoperative mortality…
It is expected that functional status and health status is impaired in COVID-19 patients after hospital discharge and that this will improve after a multidisciplinary rehabilitation program.
TKR with large migration in the last 2 PO years show a larger inducible migration compared with TKR with little to no migration in the last 2 PO years
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…