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In the first 6 months Liraglutide affects weight more than CBT, but CBT provides weight maintenance after 12 months.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
Increased cardiac sympathetic activity is highly prevalent among patienst with chronic heart failure. The increased cardiac sympathetic activity as assessed with 123I-metaiodobenzylguanidine (MIBG) is a usefull tool to discriminate responders (i.e.…
Artificial dynamic lightening can positively influence the sleep/wake cycle and reduce the disturbance of the circadian rhythm due to hospitalization.
Necessity: A study on chronic pain in persons with Down syndrome is clinical relevant for 5 reasons: 1. The neuropathology of Down syndrome without and with dementia affects pain-related gray and white matter, which may alter pain experience; 2. The…
Compared to usual care, a new perioperative care program will improved recovery and accelerated resumption of (work)activities. Resumption of work contributes significantly to QOL and will prevent disability due to general and mental health problems…
This study is a phase I trial, testing the safety and toxicity of allogeneic NK cell infusions with an escalating dose of ex vivo expanded NK cells following immunosuppressive conditioning therapy in elderly patients with AML.
After training one arm with a prosthetic simulator it is expected that the other arm will improve.
The OptiScanner provides accurate blood glucose levels in critically ill patients.
Publishing a guideline is not enough. An implementation strategy is needed to improve pain reporting, pain measurement and adequate pain therapy.
Higher occlusion rate in the EVLA group seen at 1 week postoperative. More recurrences seen in the VNUS group seen at long term. No differences in short term recovery results between both groups.
Clinically, children with syndromic craniosynostosis seem to have an increased risk of learning disabilities and behavioral problems in comparison with the general population.
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According to the WHO, patients who can benefit from palliative care should be identified earlier to enable proactive palliative care. Up to now this hardly has been addressed in scientific literature. Therefore, the aim of our study is to determine…
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Intranasal administration of cobalamin can be used as an alternative for the standard intramuscular injection of cobalamin in cobalamin deficient patients.
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
The objective is to investigate the patterns and processes of change in Acceptance-Based Behavioural Therapy (ABBT; Acceptance & Commitment Therapy + mindfulness) with chronic pain patients having high levels of psychological flexibility.…
An intervention consisting of a set of specific fatigue reducing and health enhancing advices will lead to less fatigue and sickness absence in airline pilots. Following the intervention and the accompanying advices will lead to pilots reporting…
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…