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The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
It is hypothesized that there is a significant improvement in the quality of dietary intake and physical activity in out clinic patients, with a positive iFOBT, who receive nutritional and physical activity advice via the web-based Eetscore…
It is hypothesized that the orientation of the lower limb joints are not parallel to the walking direction and that a standing measure is highly correlated with the orientation during the standing, load bearing, phase of the gait cycle.
The hypothesize is, that treatment with induction chemotherapy will lead to a 15% increase of the R0 resection rate compared to treatment with neoadjuvant chemoradiotherapy and surgery alone.
Using Irreversible Electroporation on locally advanced pancreatic adenocarcinoma deemed unresectable during explorative laparotomy, will increase progression free survival and median overall survival.
We hypothesize that with Gd-MRI inhomogeneity of lung perfusion can be readily identified and that these areas match areas of trapped air as visualized by proton MRI and CT.