185 resultaten
fetal heart deformation and its development throughout pregnancy can be measured by speckle tracking. Fetal heart deformation might be different in pregnancies complicated by placental dysfunction.
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
By using weekly the clinical rule reporter as the medication review system, the number of hospital readmissions in older patients (> 60 years) will be reduced with 5% (from 20% to 15%). For the Netherlands this may translate into prevention…
We hypothesize that in current dermatological practice, there is a undisclosed burden of psoriatic arthritis in psoriasis patients. We wish to discover the prevalence of known and unknown arthritis in these patients, and find clinical and…
Postoperative change in deltoid volume following reverse shoulder arthroplasty is related to functional outcome
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
We hypothesize that participation in an exercise program during adjuvant chemotherapy has reduced cardiovascular toxicity toxicity in women wiht breast cancer after an average follow-up of 6 years. In addition to cardiovacular toxicity, we…
We want to examine the effects of both the adjustable rocker profile and the self-adjusting insole on in-shoe pressure in this patient group. We expect to find similar reductions in pressure as previously found in healthy subjects. Also, the…
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
Group receiving Friso Comfort Next (with milk fat and mixture of different length prebiotics) will have a lower % of all hard stools reported during the 2-mo study period compared to another Young Child Formula (with partially hydrolysed whey…
Stress affects brain function in various ways. It is also associated with an increased likelihood of seizures in patients with epilepsy. The pathophysiology of this relationship is not well understood. A candidate mechanism is infraslow brain…
Routine admission to the ICU after pulmonary surgery may not necessarily be required for each patient. The aim of this study is to identify which patients may benefit from admission to the ICU after pulmonary surgery and to develop a clinical…
The proxy-patient perspective outcome has a higher level of agreement with the outcome of the self-completed EQ-5D-5L, compared with the proxy-proxy perspective outcome in mentally healthy patients.
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…