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In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.
This study aims to underpin the delivery of longstanding exercise therapy in the subgroup of patients with axSpA and complex disability. There are 3 research questions to be addressed: 1. Is longstanding, optimized active exercise therapy more…
We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
An ICT-supported, integrated, multidisciplinary treatment of COPD in primary care compared to usual care in primary care practices will improve the quality of life of COPD patients at an acceptable level of cost-effectiveness.
Pakravan's technique is a new minimal invasive surgical technique for grade 2 to 4 hemorrhoids that fail conservative treatment. As in stapling, Pakravan's technique comprises a hemorrhoidopexy with the intention of preserving important…
In patients with non-insulin dependent type 2 diabetes, intensive, short term physical activity is associated with decreased blood glucose levels and number of cardiovascular complications. In patients who are insulin dependent however, the effects…
Development of early-onset dementia (EOD) is very radical and disabling for both patient and family, due to the still prominent role of the patient in society. Except for knowledge on cognitive disorders not much is known about other disabling…
We hypothesize that atopiform dermatitis is a separate entity with specific characteristics, which needs recognition in order to be diagnosed and treated appropriately.
In this noninferiority trial it will be tested if stepped care for chronic fatigue syndrome (CFS) is noninferior to care as usual with respect to its effect on fatigue severity. Stepped care will be formed by: 1) web-based cognitive behaviour…
To compare effectiveness of interventions for insomnia and their possible secondary gain of preventing depression.
We postulate that exhaled breath sampling by an electronic nose can distinguish and adequately identify smell-prints from: 1. Atopic patients without airway obstruction 2. Non-atopic patients without airway obstruction 3. Atopic patients with…
We hypothesize that compared to treatment as usual (TAU), Yoga-based Therapy (YBT)+TAU will lead to: Hypothesis 1: Greater reductions in depressive symptoms, assessed with (a) clinician-administered measures (Hamilton Depression Rating Scale) and (…
The aim of this study is to demonstrate that procedural sedation with propofol and esketamine is more effective and will result in less cardiopulmonary depression than sedation with propofol and the opioid alfentanil. Less side effects should also…
We hypothesize that 18F-FDG is a valide marker for metabolic activity in adipose tissue and even more pronounced in type 2 diabetes.
The protein status of an individual effects food preferences and intake. If the protein status is low, products high in protein will elicit greater reward.