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Survival of patients treated with hepatic arterial infusion pump chemotherapy will be superior to that of a historical cohort with similar patient characteristics
The overall aim of this proposed study is to gain insight into the target attainment of the administered antibiotics during the two-stage arthroplasty exchange, in order to determine the efficacy in relation to the minimal inhibitory concentration (…
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
It is expected that HFNC therapy will speed up the recovery of an exercise induced lung function decline. We speculate that the time to recovery to their normal lung function will be halved.
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
An activity tracker improves preoperative gait speed in elderly colorectal cancer patients compared to a standard prehabilitation program
Non-inferiority of omission of PCI prior aortic valve replacement by TAVI
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
Not applicable
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
Acute complex skin defects will heal using a dermal substitute (Glyaderm).
The school-based sleep intervention is effective in improving self-reported sleep quality.
We hypothesize more than 90% of the participants in the in-hospital, standard-of-care follow-up will contact the hospital during the study period and 40-50% of the patients in the patient-led, home-based follow-up will contact the hospital between…
It is hypothesized that in a primary health care population, a more condensed form of schema therapy (ST) might be sufficient for an effective reduction of personality problems.
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
There are multiple ways of weaning from venovenous ECMO support
By dosing Ampligen every other day intranasally, it is believed that SARS-CoV-2 can be inhibited at the point of entry, and thus will be much less likely to progress to a pulmonary infection, or moderate COVID-19 disease.
We hypothesize that two additional face-to-face counseling sessions, in which several psychological techniques will be practiced, will support the participating patient-couples towards a significant and more sustainable lifestyle change compared…
This study aims to describe the usability in clinical practice of the validated Dutch translation of the optimized OBAS. Further, the MCID will be determined for application of the OBAS in later clinical trials.
We hypothesize that the combination of both the IPS and PA intervention is more effective than each of the interventions separately (IPS, or PA), i.e. ‘1+1 = 3’