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Divergent Low Level Laser Therapy as novel treatment for oral mucositis in pediatric cancer patients
What is the effect of divergent LLLT on the number of days of mucositis > grade 1?
Two often-iterated and relatively widespread, but probably too narrow, views of testosterone are that (a) it is first and foremost a "social" hormone, and that (b) higher levels of testosterone are associated with mainly negative…
With the quantification of circulating tumor DNA treatment response assessment will improve in metastatic prostate cancer patients.
Prosthetic Heart Valve (PHV) endocarditis is complicated by peri-annular extension (abscesses/mycotic aneurysms) in up to 50% of patients and has an in-hospital mortality of approximately 30%. However, with current standard imaging tools such as…
Multicomponent prehabilition can reduce postoperative delirium and other postoperative adverse events
The aim of this study is to investigate an abridged version of an online health training, based on cognitive behavioral therapy components, that is focused on the optimization of health. It is expected that this online health training will have a…
This study will be an open observational study with the objective to test the feasibility of the mDLS. The variability of the methodology over time will be assessed. Blood flow and coagulation status assessed by mDLS and LSCI will be compared with…
1. We expect the ST/SPSP-50 condition to be more effective than ST/SPSP-25 condition on depression outcome and/or characterological symptoms. 2. No differences in outcome are expected between ST en SPSP and we don’t expect the type of treatment to…
Given the fact that behavior is for the largest part driven by the context that we live in, sit-stand workstations in the classroom may invite and seduce children to be more active and reduce sedentary time at school. If sit-stand workstations…
Delayed fluorescence imaging is optimal for visualization of bile ducts compared to the surrounding liver.
Firstly, we hypothesise that Acceptance and Commitment Therapy (ACT) for diabetes patients will reduce depressive symptoms and will increase diabetes self-care behaviour. Furthermore, we explore the underlying operating mechanisms of ACT. We…
In this study we explore the feasibility of combined decitabine and cytarabine chemotherapy in AML and high risk MDS patients with a high risk of early mortality (day 30 mortality) during standard induction chemotherapy (HCT-CI co-morbidity index…
Studies on PSMA PET/CT the past few years are promising but often of retrospective nature and with heterogeneous patient populations. In our academic centre there are currently two trials running with 18 F-FDHT PET/CT. Results are promising, but…
Performing a standard laboratory package prior to the first visit to the outpatient clinic rather than performing laboratory tests afterwards will lead to a shorter time until the diagnosis has been established.
We hypothesize that a low heart rate variability and baroreflex sensitivity in the pre- or postoperative phase are associated with orthostatic intollerance when compared to subjects with normal heart rate variability.
Narcotrend Index (Depth of Hypnosis Index, derrived from EEG) guided application of propofol may result in faster emergence after procedural sedation for gastrointestinal endoscopy in paediatric patients aged between 1 and 12 years
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
Stand-alone internet-based Vestibular Rehabilitation (VR) and internet-based VR with physiotherapeutic support is more (cost-)effective than usual care when treating dizziness in older patients in general practice.