425 resultaten
We hypothesize that before clinical manifestation of NEC, urine I-FABP, serum GLP1/2, faecal Calprotectin, faecal TLR4 (on shedded enterocytes) and faecal bile acids can be used as predictive markers for NEC. We also hypothesize that Near Infrared…
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(1) When using the lower leg axis as a reference, the CT-based femoral component rotation with Zimmer Gender-Solutions patellofemoral joint replacement is 3 to 6 degrees external relative to the transepicondylar axis. (2) The short-term (less than…
In this study we explore the feasibility of the sequential use of FLAMSA chemotherapy and T cell depleted reduced intensity conditioning allogeneic stem cell transplantation followed by donor lymphocyte infusion at 3 and 6 months after…
Type and intensity of the tasks trained influence the training effects while using a myo-electric prosthesis.
The primary hypothesis is that normo-ovulatory women with a BRCA mutation have lower levels of AMH compared to normo-ovulatory BRCA mutation-negative women, with at least a difference of 0.40 ng/ml, suggesting an effect size of three years in…
Whole blood thrombin generation measurement is comparable to plasma thrombin generation in clinical setting.
Neo-adjuvant chemotherapy facilitates complete cytoreduction without negative effects on safety.Therby offering a possibility of better overall survival.
Tailored exercise is more effective in regaining functional ability, in comparison to usual care, in adolescents diagnosed with HMS/EDS-HT
The expectation is that the use of Medido is a substantial improvement in the treatment and that physical disabilities will decrease. Also the cost effectiveness of Medido will be taken into account.
The goal of this trial is to investigate the efficacy of the IMP during c-section with and without the use of Sufenta: As well as start of action, duration of action, the degree of motor and sensory block as well as the hight of the block itselfs…
Laparoscopic Fluorescent near-infrared imaging using ICG can accurately detect liver metastases from uveal melanoma intra operatively.
We expect an improvement in psychological flexibility and a decrease in pain interference in daily life or in fatigue. Furthermore, we expect a decrease in depression and anxiety symptoms.
An intervention with Methylphenidate, Melatonin or Light Therapy will lead to changes in visual functioning.
The objective of this study is to assess the technical feasibility of the EsoFLIP dilation balloon in the treatment of achalasia.
The per patient annual infliximab dose can be lowered in Crohn’s disease patients in stable remission using dose reduction guided by serial trough level measurements.
Injecting the upper eyelids with the anesthetic is experienced as quite painful by most patients. The acidity of the commonly used anesthetic Xylocaine is assumed to be the (main) cause of the pain. Citanest, the standard local anesthetic in…
Patients included in this trial will be diagnosed with both social anxiety disorder and avoidant personality disorder. Improvements can thus be realized on 2 different domains, namely with respect to severity of social anxiety disorder and with…
Patients who have received CRT will have more symptom reduction anda better quality of life after TAU than patients who have not received CRT. Furthermore we hypothesise that CRT will be cost-effective.
To evaluate the targeting performance (including pharmacokinetics/-dynamics) of the human radiolabeled monoclonal-antibody cytokine fusion protein 124I-F8IL10 in 5 patients with rheumatoid arthritis, in a single dose study.