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In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
The objective is to assess which Transfusion Triggers are used in Blood-conserving Trials in Lower Limb Arthroplasty and to assess the prevalence of usage of Transfusion Triggers in time.
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Women with POI have low androgen blood levels which leads to less overall sexual satisfaction, less frequent desire and more pain during sex.
Aliskiren can decrease glomerular pressure, in respect to ramipril, in patients with essential hypertension and overweight/obesity, independent from blood pressure.
1. The addition of moderate positive end-expiratory pressure (PEEP, 7.5 cmH2O) to high inspiratory fractions of oxygen can either improve oxygenation or reduce respiratory rate, or both, in patients with severe Covid-19 pneumonia 2. The application…
Randomization 1: The hypothesis to be tested is that the outcome in arm B is better than in arm A.
The aim of the CO-PRINCE study is to establish the efficacy and safety of long-term antibiotic prophylaxis with co-trimoxazole in children with recurrent upper and/or lower respiratory tract infections (including ear-nose-throat).
The physical activity condition will show a significantly stronger decrease in PTSD symptoms from pre- to post-treatment, compared to the active control condition
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…
The addition of embolization of the middle meningeal artery will reduce recurrent surgery rate in symptomatic chronic subdural hematoma patients.
Active surveillance is a reasonable treatment option for selected ALT patients
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
Combined pressure-flow measurements under hyperaemia can identify those patients with renal artery stenosis that will benefit from renal revascularization, assessed by blood pressure and renal function. The hemodynamical significance of a renal…
It is expected that Covid-19 patients, whose symptoms are considered as "mild" (i.e., who have not usually been hospitalized) can experience prolonged complaints, resulting in reduced quality of life.
We hypothesise that Endocytoscopy is feasible to detect dysplasia/carcinoma in patients with BE
Low frequency stimulation causes vasodilation in the affected extremity of patients with CRPS