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The nurse practitioner will actively approach all fracture patients above the age of 50 for screening and intensive treatment of osteoporosis. This will improve the number of fracture patients screened and treated for osteoporosis.
Acidic and neutral oligosaccharides supplemented enteral nutrition has a positive effect on infectious morbidity, modulation of the immune response, postnatal adaptation of the gut, feeding tolerance and short-term outcome in VLBW infants.
Efficacy of transfusion support depends on disease and treatment related patient factors. Markers of endothelial damage have been identified, but till today not in relation to the efficacy of transfusions.
It is hypothized that a cognitive behavioral program that in particular is focused on motivation and self-management in persons at high risk for CVD and/or DM2 will change their behavior, which reduces the risk on developing DM2 and the risk on CVD.
We hypothesize that treatment of sickle cell patients with NAC results in reduced red cell PS exposure, reduced endothelial activation, increased NO availability, reduced coagulation activation and reduced inflammation detectable with specific…
To reduce cumulative radiation dose in the rectum in prostate cancer patients who are treated with curative intent using external beam radiotherapy. We will investigate whether position correction based on implanted gold markers or re-planning based…
First randomization: The hypothesis to be tested is that the outcome in arm B (early intensification of rituximab combined with 2 weekly CHOP) is better than in arm A (no intensification of rituximab). Second randomization: The hypothesis to be…
Implementation of innovations in mental health care needs multifaceted strategies in order to improve care with better outcomes for patients. The hypothesis in this study is: teams of health care professionals participating in a Breakthrough…
Differences exist in duration of effect of insulin detemir, insulin glargine or NPH insulin on glucose production, lipolysis and proteolysis in patients with type 2 diabetes mellitus.
PAS III-PC and PR-PAS III-PC are non-inferior compared to plasma PC in terms of recovery, estimated by the 1-hour CCI post transfusion
We hypothesize that a relationship is present between functional connectivity, network features and neurocognitive performance in GBM patients. We also expect treatment and recurrence of the tumor to lead to remodeling of the neuronosynaptic maps…
The use of parenterally administered LEV in neonatal epileptic seizures, detected electrographically, with or without clinical signs, will be safe, and pharmacokinetic and –dynamic properties of the use in neonates will be determined.
Affective disorders (i.e. depressive or anxiety disorders) of dementia caregivers are largely preventable.
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
The primary objective of the study is to study the safety of MMR booster vaccination in JIA patients by measuring JIA disease activity and the occurrence of measles, mumps or rubella infection. The next primary objective is to evaluate the efficacy…
It is hypothesized, that mental practice embedded in daily multi approach therapy in Nursing Homes will improve daily activities of adult stroke patients more and/or faster compared to therapy as usual alone.
Administration of levothyroxine at bedtime significantly changes TSH and thyroid hormone levels compared to morning administration. Quality of life will improve with bedtime administration
The new preventive intervention will lead to a significant decrease in psychological problems and perceived stress, an improvement in the quality of life of the informal care-givers as compared with a waiting list control group.
Chemosensitization with capecitabine improves the percentage of patients with objective tumor responses who are also treated with 177Lu-octreotate.
Selfmanagement coaching by an expert patient leads to more control and better quality of life in newly diagnosed patients with diabetes type 2. Selfmanagement coaching by an expert patient leads to better coping in newly diagnosed patients with…