699 resultaten
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
Half dose Urokinase (50.000IE/h) will significantly reduce hemorrhagic complications compared with the standard dose Urokinase (100.000IE/h) with comparable technical success rate
Stromal Vascular Fraction enriched lipofilling in combination with Platelet Rich Plasma (PRP) increases skin quality improvement as compared to lipofilling in combination with PRP alone.
The outcome in patients with removal on demand is not inferior to the outcome in patients with routine removal. By omitting routine removal a reduction in costs will be achieved
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up
1) The CHIP-Family intervention will result in improved parental mental health and child psychosocial wellbeing (i.e. less behavioral/emotional problems). 2) Parents with poor mental health and children with poor psychosocial wellbeing will benefit…
The aim of the study is to enhance pharmacotherapeutic effects in patients with recent-onset rheumatoid arthritis by means of pharmacological conditioning with or without an online guided health training. It is expected that the interventions will…
In normal weight and overweight/obese young males we expect that - when compared to a single bout of prolonged sitting: (1) sitting on a stability ball will attenuate cardiometabolic health effects; (2) 10-min standing interruptions will not…
The online treatment i-Sleep effects not only directly sleep related complaints but also helps alleviate depression symptoms
The main hypothesis is that compared to TAU, BA will be more effective and less costly. A secondary goal is to explore several potential mechanisms of change, as well as predictors and moderators of treatment outcome of BA for late-life depression.
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy in patients with recurrent GBM with an acceptable toxicity profile, compared to lomustine.
Implementation of Syncope Algorithms (SAs) in the Netherlands will increase diagnostic yield, avoid unnecessary admissions and improve quality of life (QoL) by offering timely diagnosis & treatment
Active2Gether effectively increases levels of physical activity in young adults.
We hypothesize that compared to treatment as usual (TAU), Yoga-based Therapy (YBT)+TAU will lead to: Hypothesis 1: Greater reductions in depressive symptoms, assessed with (a) clinician-administered measures (Hamilton Depression Rating Scale) and (…
Magnetic Resonance Direct Thrombus Imaging (MRDTI) can be an accurate test for diagnosing Upper Extremity Deep Vein thrombosis (UEDVT)
To establish which BRT or combination of BRTs is the fastest, least painful and has the lowest complication rate for adult patients with an anterior shoulder dislocation presenting in the emergency department (ED).
Intracranial atherosclerosis is an important cause of ischemic stroke and transient ischemic attack (TIA). Ischemic stroke or TIA in the posterior circulation accounts for approximately 20 to 30% of all ischemic events. We hypothesize that arterial…
Virtual Reality (VR) as distraction technique is promising as pain relief. The extent to which VR is effective in relieving pain depends on the extent of presence in the virtual world. This study investigates if the quality of different executive…
It is hypothesized that the Silbernagel exercise program yields at least similar results in terms of symptom reduction (VISA-A score and VAS score)compared with the Alfredson eccentric exercise program.
Our hypothesis is that our gradually progressive protocol offers advantages with respect to the eccentric protocol based on the protocol of Alfredson (gold standard). We expect that, because this protocol is more individualized, less pain during the…