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The hypothesis is that the injury rate, severity and burden of injury over one-season is lower among youth volleyball players using ‘VolleyVeilig’ than among youth volleyball players not using ‘VolleyVeilig’ (volleyball as usual).
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
The effects of a brief compassion induction exercise will be compared to the effects of a neutral exercise. We hypothesize that a brief compassion induction in a sample of patients with PD will facilitate the choice of more adaptive emotion…
The knotted grip placement technique of proseal laryngeal mask shall ease its placement in patients undergoing general anesthesia for elective surgeries.
Reducing the dose in the setting of therapeutic drug monitoring (TDM) does not affect clinical disease activity and safety, while it will reduce costs.
The aim of this study is to assess long term scar quality of deep dermal burns after debridement with hydrosurgical excision versus conventional tangential excision.
The YEARS algorithm is non-inferior to management by CTPA with regard to 3-month recurrent VTE rates and will reduce the rate of unnecessary CTPA in patients with clinically suspected PE and active malignancy.
LEND surgery is a (cost)-effective treatment option for patients with Diabetes and lower extremity compression neuropathy, compared to conventional (non-surgical) care.
A switch to thrombininhibitor dabigatran or addition of tranexamic acid to the factor Xa inhibitor may be effective in women who experience heavy menstrual bleeding during anticoagulant treatment with factor Xa inhibitors.
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…
Training therapist in optimized ROM (Feedback Informed Treatment) and Shared Decision Making will result in less drop-outs, better outcomes, better patient experience and more favourable attitude ot therapist towards Routine Outcome Monitoring
A comprehensive multisiciplinary lifestyle intervention program reduces the risk of recurrent cardiovascular events in patients who have suffered an acute coronary syndrome.
The clinical efficacy of the PENG block is superior to the femoral nerve block
The banded gastric bypass might be a possible therapy to increase weight loss and decrease long term weight regain in the super morbidly obese patients.
Since bleeding risk is high in the elderly we hypothesize that clopidogrel is superior to ticagrelor and prasugrel in terms of causing lesser bleeding events and being non inferior in net clinical benefit in patients above 75 years and CRUSADE…
1. We hypothesize that well-trained strength athletes (using AAS) will have significantly greater organ volume when compared to well-trained strength athletes (not using AAS) and recreationally active participants (not using AAS). 2. We hypothesize…
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Participants in the intervention group will show a larger decline in household chaos than participants in the control group. As a result parenting quality in the intervention group will improve more than in the control group. Secondary hypotheses…
"De Nieuwe Toekomst" will empower female victims of intimate partner violence by making them financial independent which reduces the risk of intimate partner violence victimisation