602 resultaten
The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
The hypothesis is that stratification of the referred population by the two referring screening radiologists using a validated design (BI-RADS, screening variant) can lead to a fast track workflow with only imaging tools, which would enable us to…
A first hypothesis is that an advanced quality improvement program (AQIP) significantly improves clinical outcomes in persons with type 2 diabetes compared to a usual quality improvement program (UQIP). The second hypothesis is that persons with…
Endoveneus laser treatment op the small saphenous vein is compareble to crossectomy with regard to recurrence and therapy failure.
To investigate whether the clinical outcome is similar after the implantation of the Endeavor Resolute stent versus the XIENCE V stent (non-inferiority test).
Blood transfusions at home instead of in the hospital are feasible, lead to higher quality of life of patients and are safe at no higher costs.
The infusion of intrathecal baclofen using higher flow rates results in more extensive intrathecal distribution, hence benefits pharmacodynamic properties of baclofen
Wet-wrap treatment with diluted corticosteroids is more effective than wet-wrap treatment with emollients only
What is the effectiveness of Diclofenac compared to Paracetamol over a period of two weeks and if necessarily another two weeks (consistent with the Dutch guidelines for general practitioners) in new consulters with knee osteoarthritis in the…
Primary research question: Is there a difference in effectiveness and costs of clozapine treatment compared to olanzapine treatment in the reduction of substance use disorders of patients with schizophrenia and related psychotic disorders?…
With usage of mesh material (Avaulta anterior) in the treatment of a cystocele >/ 2 with complaints a better anatomical result is achieved in comparence with the standard treatment (anterior colporraphy).
We hypothesize that expiratory Volatile Organic Compounds analysis by an electronic nose is capable of discriminating between asymptomatic infants and infants with respiratory wheeze.
A physical reactivation program is more effective in improving physical activity behaviour, quality of life, diabetic parameters and psychosocial well being than usual care in type-2 diabetic patients.
ECT is effective as treatment of psychosis in patients suffering from clozapine resistant schizophrenia.
Immuune suppression therapy (azathioprine or 6-Mercaptopurine) maintenance therapy is as effective as infliximab maintenance therapy after remission induction with combined infliximab/immune suppression therapy for at least 6 months.
We hypothesise that regret is affected by adverse outcomes of the cancer treatment and not by patient involvement in the treatment choice.