29 resultaten
Assess the safety and tolerability of single ascending IV bolus doses of ABP-700
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
Patients who received CBM-I training will start their exposure therapy with lower anxiety levels, and their anxiety levels will reduce faster compared to patients that receive a placebo training.
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
Cabozantinib improves overall survival in patients with hepatocellular carcinoma compared with placebo
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
Intranasal administration of palivizumab is safe in healthy adult volunteers
Stimulation of the right DLPFC of alcohol dependent patients will decrease self-reported craving and recude relapse rates. Furthermore it will increase behavioral control and normalize brain activation patterns.
Varenicline reduces craving to cocaine and/or impulsivity in human cocaine users.
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
Nasal administration of palivizumab in late preterm infants reduces RSV infection
We hypothesize that exposure to the user-tailored, dynamic lighting condition will stabilize or reduce alcohol consumption and craving in comparison to a control condition with regular lighting.
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
1) Pre-sleep whey protein ingestion stimulates overnight muscle protein synthesis rates 2) Pre-sleep casein protein ingestion stimulates overnight muscle protein synthesis rates 3) Pre-sleep whey and casein protein do not differ in their impact on…
-We expect that the youth who receive an active CBM training on top of care-as-usual show a greater reduction in cannabis or alcohol misuse at follow up when compared their general population peers. -We expect that CBM training works by reducing…
We hypothesized that methylphenidate will improve certain aspects of language comprehension and creativity.
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
The implementation of antimicrobial coatings in health care results in an improved hygienic environment to support patient recovery and lowers the risk of a health care associated infection.
We hypothesize that Iberogast reduces heartburn in patients with functional dyspepsia through an effect on both oesophageal hypersensitivity to acid and on the incidence of reflux episodes.