328 resultaten
We hyopthesize that in SCCH patients 3-monthly pamidronate decreases locally increased bone turnover (measured by Na18F-PET scans) and thereby decreases pain, and leads to improvement in shoulder girdle function, quality of life, physical and work…
1. There will be a significant improvement in cognitive control, attention bias and memory bias performance after completion of the selected training module in the active vs. control training. 2. Rumination and depressive symptom severity will…
We hypothesize that the use of intrathecal morphine reduces postoperative pain and opioid consumption, which in turn will reduce the incidence of delirium.
This is a FIH study for M528101. We expect that the compound is safe and tolerable.
We hypothesis that collagen supplementation augments the benefits of jumping exercise for bone metabolism.
Objectives Part A: • To evaluate the safety and tolerability of CIT-013 after administration of single, ascending, IV doses in healthy volunteers. • To evaluate the pharmacokinetics of CIT-013 after administration of single, ascending, IV doses in…
We expect better outcomes: ABC > CBM > sham-CBM
As the pain quality item “unpleasantness” delineates EB pain, we hypothesize the modulation of affective pain processing in the brain by way of intervention with Transvamix (a CBM comprising THC and CBD) - objectified by functional magnetic…
The goal of this trial is to investigate whether (and at which dose or ratio) CBD has a modulating effect on the psychotropic effects of THC by comparing the effects of THC to the combination of THC with CBD in a range of ratios. Simultaneously,…
We hypothesize that the ingestion of both lesser mealworm and whey protein (30 g per day for three subsequent months) will lead to less muscle damage upon the repeated physical exercise compared to the iso-caloric placebo.
To reduce fatigue symptoms with the use of a bovine lactoferrin supplement in patients suffering from Long COVID.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
Onderzoeken of drie weken lang CBD spanningsklachten kan verminderen bij hersentumorpatiënten in de stabiele fase kan verminderen, en zo kwaliteit van leven kan verbeteren. Depressieve klachten, slaap/vermoeidheid en algehele kwaliteit van leven…
By dosing Ampligen every other day intranasally, it is believed that SARS-CoV-2 can be inhibited at the point of entry, and thus will be much less likely to progress to a pulmonary infection, or moderate COVID-19 disease.
To evaluate the safety and tolerability of AP30663 in healthy males at doses up to 12mg/kg
Our hypothesis is that the efficacy of FMT in patients with active UC can be increased by: 1. Pretreatment with budesonide in patients with active UC, which may reduce inflammation prior to infusion of the donor feces solution. This reduced…
To investigate the safety, tolerability and pharmacokinetics after multiple daily doses of YTX-7739
A direct patient feedback system can lead to earlier detection of pain and a more timely treatment resulting in improved patient reported outcomes on postoperative pain.